Yuan Fang, Lu Aili, Wu Shibiao, Wang Lixin
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Front Neurol. 2020 Nov 30;11:580777. doi: 10.3389/fneur.2020.580777. eCollection 2020.
Refractory status epilepticus (RSE) is a critical and intractable neurological emergency. Around 55% of RSE episodes still persist despite high dose of continuous infusion of anesthetics. It's a clinical urgency and challenge to search for novel alternative treatments to control RSE as soon as possible. Here, we reported a case of RSE in a 67-year-old woman with varicella-zoster virus encephalitis. She had persistent non-convulsive SE despite the continuous infusion of midazolam. On the basis of fundamental treatments, she was given electroacupuncture at Shuigou acupoint for 10 min. An immediate EEG suppression was seen after the electroacupuncture treatment and lasted for 9 min, and lasting epileptic discharges (> 10 s) and clinical seizures were not observed any more. Midazolam was withdrawn gradually 24 h later. This case report may bring an alternative treatment for RSE.
难治性癫痫持续状态（RSE）是一种危急且棘手的神经急症。尽管大剂量持续输注麻醉剂，仍有大约55%的RSE发作持续存在。尽快寻找新型替代疗法来控制RSE是一项临床急症和挑战。在此，我们报告了一例67岁患有水痘-带状疱疹病毒脑炎的女性RSE病例。尽管持续输注咪达唑仑，她仍存在持续性非惊厥性癫痫持续状态。在基础治疗的基础上，对她的水沟穴进行了10分钟的电针治疗。电针治疗后立即观察到脑电图抑制，持续了9分钟，且未再观察到持续的癫痫放电（>10秒）和临床发作。24小时后逐渐停用咪达唑仑。该病例报告可能为RSE带来一种替代治疗方法。
