Martini P F, Segoloni G P, Giachino G, Jeantet A, Triolo G, Mangiarotti G, Giacchino F, Messina M
Minerva Med. 1977 Aug 18;68(38):2667-93.
The literature on primary and secondary hyperparathyroidism is surveyed in the presentation of an account of the present positon. Reference is also made to personal clinical experience, particularly in secondary cases. The physiopathology of parathormone, calcitonin and vitamin D is described; the last, in fact, has proved useful in the treatment of secondary forms. The usual symptomatological tests of performance are explained, together with their diagnostic value. The clinical symptoms and their physiopathological significance are also illustrated. Stress is laid on the importance of conservative management in secondary forms. Good results now enable parathyroidectomy to be avoided or delayed in many cases.
本文在阐述当前状况时对原发性和继发性甲状旁腺功能亢进的文献进行了综述。文中还提及了个人临床经验,尤其是继发性病例的经验。描述了甲状旁腺素、降钙素和维生素D的生理病理学;事实上,维生素D已被证明在继发性甲状旁腺功能亢进的治疗中很有用。解释了常用的症状学检查及其诊断价值。还阐述了临床症状及其生理病理学意义。强调了继发性甲状旁腺功能亢进保守治疗的重要性。目前良好的治疗效果使得在许多病例中能够避免或推迟甲状旁腺切除术。