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2020 年回顾:白塞综合征。

One year in review 2020: Behçet's syndrome.

机构信息

Division of Rheumatology, Department of Internal Medicine and Behçet's Disease Research Centre, Istanbul University-Cerrahpasa, School of Medicine, Istanbul, Turkey.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

出版信息

Clin Exp Rheumatol. 2020 Sep-Oct;38 Suppl 127(5):3-10. Epub 2020 Dec 10.

Abstract

Behçet's syndrome is a variable vessel vasculitis with multi-system involvement that shows important heterogeneity among patients regarding demographic features, organ manifestations, frequency and severity of relapses, disease course, response to treatment and prognosis. This heterogeneity has made it difficult to interpret and compare the results of studies, to standardise disease assessment and to develop management strategies. Several new studies have been published during the previous year exploring the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of Behçet's syndrome. The aim of this review is to provide an overview of the most relevant recent research in Behçet's syndrome from a critical perspective.

摘要

贝赫切特综合征是一种多系统受累的可变血管炎,患者在人口统计学特征、器官表现、复发频率和严重程度、疾病过程、治疗反应和预后等方面存在显著异质性。这种异质性使得解释和比较研究结果、标准化疾病评估以及制定管理策略变得困难。在过去的一年中,已经发表了几项新的研究,探讨了贝赫切特综合征的流行病学、发病机制、临床表现、诊断和治疗。本文的目的是从批判性的角度对贝赫切特综合征的最新研究进行综述。

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