Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
J Appl Clin Med Phys. 2021 Jan;22(1):293-298. doi: 10.1002/acm2.13122. Epub 2020 Dec 17.
We analyzed the clinical and imaging characteristics of patients with breast ductal carcinoma in situ with microinvasion (DCISM) and breast ductal carcinoma in situ (DCIS).
We analyzed the records of 40 patients diagnosed with DCISM and 61 patients with DCIS who were hospitalized at Shengjing Hospital (Shenyang, China) from January 2009 to June 2016. The size, hardness, and degree of calcification of tumors were determined by mammography and ultrasonography.
In all, 37 DCISM patients and 45 DCIS patients showed clinical palpable masses (92.5% vs 73.77%, P = 0.018). Mammography showed that the mean size of tumor was larger in DCISM patients than that of DCIS patients (3.13 ± 1.51 vs 2.68 ± 1.77, P = 0.030). Ultrasound examination revealed calcification shadows in the solid tumor mass in 17 DCISM cases and 11 DCIS patients (42.5 vs 18.03%, P = 0.007). Furthermore, estrogen receptor positivity and progesterone receptor positivity were more common in DCIS patients (32.5% vs 54.10%, P = 0.033; 22.5% vs 45.90%, P = 0.017), and the percentage of menopausal patients were higher in DCISM patients than that of DCIS patients (70.00% vs 47.54%, P = 0.026).
Clinically palpable and calcified tumor masses on sonography are more commonly encountered in DCISM lesions.
我们分析了微浸润性导管癌（DCISM）和导管原位癌（DCIS）患者的临床和影像学特征。
我们分析了 2009 年 1 月至 2016 年 6 月在沈阳盛京医院住院的 40 例 DCISM 患者和 61 例 DCIS 患者的记录。通过乳腺 X 线摄影术和超声检查确定肿瘤的大小、硬度和钙化程度。
共有 37 例 DCISM 患者和 45 例 DCIS 患者出现临床可触及肿块（92.5%比 73.77%，P=0.018）。乳腺 X 线摄影显示，DCISM 患者的肿瘤平均大小大于 DCIS 患者（3.13±1.51 比 2.68±1.77，P=0.030）。超声检查显示 17 例 DCISM 病例和 11 例 DCIS 病例的实体瘤内有钙化阴影（42.5%比 18.03%，P=0.007）。此外，雌激素受体阳性和孕激素受体阳性在 DCIS 患者中更为常见（32.5%比 54.10%，P=0.033；22.5%比 45.90%，P=0.017），而处于绝经期的患者在 DCISM 患者中比 DCIS 患者中更为常见（70.00%比 47.54%，P=0.026）。
临床上可触及和超声钙化瘤块在 DCISM 病变中更为常见。
