İstanbul University-Cerrahpaşa, Faculty of Health Sciences, Department of Audiology, İstanbul, Turkey.
Sağlık Bilimleri University, Hamidiye Faculty of Health Sciences, Department of Audiology, İstanbul, Turkey.
Int J Pediatr Otorhinolaryngol. 2021 Feb;141:110555. doi: 10.1016/j.ijporl.2020.110555. Epub 2020 Dec 11.
The primary aim of this study is to investigate whether the electrical stimulation of the second ear causes a difference in electrically evoked auditory brainstem responses (eABR) between two ears over time.
The study included thirteen subjects under the age of five who used cochlear implants for at least six months in the first ear prior to the sequential cochlear implantation. Postoperative eABRs were conducted on the 1st (first fitting of the second speech processor), 3rd, and 6th months of the second implantation in the basal, medial, and apical electrode positions. The recording was started with the second cochlear implant (CI2), and then the first cochlear implant (CI1) was tested. Sound field audiometry and receptive/expressive language assessments were also performed at 1 and 6 months after the second cochlear implantation.
eABR results indicate that when eV wave latencies are examined for all electrodes, CI2 is significantly longer than CI1 (p < 0.05). When eV wave amplitudes are examined for all electrodes, CI1 is significantly higher than the CI2 (p < 0.05). eV latency and amplitude changes between both implants were examined up to six months after implantation. Statistically significant changes were observed in the basal, medial, apical electrode for eV wave latencies, and only in the medial electrode for eV wave amplitudes (p < 0.05). Average sound field thresholds and receptive/expressive language scores improved statistically significantly for all subjects at the end of the study (p < 0.05).
The postoperative eABR test is a valuable test battery that provides the clinician with important ideas about the estimated threshold, comfortable and audible sound level, CI performance, and auditory pathways up to the brainstem. Since the maturation is still ongoing, an extended period longer than six months is needed to evaluate interaural differences.
本研究的主要目的是探讨刺激第二耳是否会导致双耳电诱发听觉脑干反应（eABR）随时间的变化而产生差异。
本研究纳入了 13 名年龄均在 5 岁以下的受试者，这些受试者在双耳序贯人工耳蜗植入前，均已在第一耳使用人工耳蜗植入装置至少 6 个月。在第二耳植入后的第 1 个月（第二言语处理器的首次适配）、第 3 个月和第 6 个月，分别在基底、中间和顶端电极位置进行术后 eABR 检查。记录首先从第二人工耳蜗（CI2）开始，然后测试第一人工耳蜗（CI1）。在第二人工耳蜗植入后 1 个月和 6 个月还进行了声场听阈和接受/表达性语言评估。
eABR 结果表明，当检查所有电极的 eV 波潜伏期时，CI2 显著长于 CI1（p<0.05）。当检查所有电极的 eV 波振幅时，CI1 显著高于 CI2（p<0.05）。检查了两个植入物之间的 eV 潜伏期和振幅变化，直到植入后 6 个月。eV 波潜伏期在基底、中间和顶端电极，以及 eV 波振幅仅在中间电极，均观察到统计学显著变化（p<0.05）。在研究结束时，所有受试者的平均声场阈值和接受/表达性语言评分均有统计学显著改善（p<0.05）。
术后 eABR 测试是一种有价值的测试组合，可为临床医生提供有关估计阈值、舒适和可听声音水平、CI 性能和听觉通路至脑干的重要信息。由于成熟仍在进行中，需要更长的时间（超过 6 个月）来评估双耳间的差异。
