Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
J Surg Oncol. 2021 Feb;123(2):521-531. doi: 10.1002/jso.26311. Epub 2020 Dec 17.
The incidence of soft tissue complications following sarcoma surgery in the upper extremity is reportedly high. Therefore, this study assessed the National Surgical Quality Improvement Program (NSQIP) database to identify independent risk factors, while also reporting the incidence of soft tissue complications in the first 30 days after surgery.
A total of 620 patients that underwent surgical treatment for upper extremity sarcoma were included from the NSQIP database. Soft tissue complications were defined as surgical site infection, wound dehiscence, or soft-tissue related reoperations. Clinically relevant patient and treatment characteristics were selected and analyzed.
The 30-day soft tissue complication rate was 4.7%. In the multivariable analysis, higher body mass index (p = .047) and longer operative times (p = .002) were independently associated with soft tissue complications.
Higher body mass index and longer operative times are risk factors for soft tissue complications following upper extremity sarcoma surgery. The soft-tissue complication rate following resection of upper extremity tumors is low in this national cohort, possibly due to the relatively small tumor size and low prevalence of radiotherapy.
据报道，上肢肉瘤手术后软组织并发症的发生率较高。因此，本研究评估了国家外科质量改进计划（NSQIP）数据库，以确定独立的风险因素，并报告手术后 30 天内软组织并发症的发生率。
从 NSQIP 数据库中纳入了 620 例接受上肢肉瘤手术治疗的患者。软组织并发症定义为手术部位感染、伤口裂开或与软组织相关的再次手术。选择并分析了有临床意义的患者和治疗特征。
30 天软组织并发症发生率为 4.7%。在多变量分析中，较高的体重指数（p=0.047）和较长的手术时间（p=0.002）与软组织并发症独立相关。
较高的体重指数和较长的手术时间是上肢肉瘤手术后软组织并发症的危险因素。在这个全国性队列中，上肢肿瘤切除术后的软组织并发症发生率较低，可能是由于肿瘤相对较小且放射治疗的发生率较低。
