Di Renzo Maria Flavia, Corso Simona
Department of Oncology, University of Torino, 10124 Torino, Italy.
Candiolo Cancer Institute, FPO-IRCCS, Candiolo, 10060 Torino, Italy.
Cancers (Basel). 2020 Dec 15;12(12):3779. doi: 10.3390/cancers12123779.
For many decades, basic and preclinical cancer research has been based on the use of established, commercially available cell lines, originally derived from patients' samples but adapted to grow indefinitely in artificial culture conditions, and on xenograft models developed by injection of these cells in immunocompromised animals [...].
几十年来，基础和临床前癌症研究一直基于使用已建立的、可商购的细胞系（最初源自患者样本，但已适应在人工培养条件下无限生长）以及通过将这些细胞注射到免疫受损动物中建立的异种移植模型[……]。
