Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK.
Department of Trauma and Orthopaedics, Queen Elizabeth University Hospital, Glasgow, UK.
Hip Int. 2022 Nov;32(6):717-723. doi: 10.1177/1120700020981573. Epub 2020 Dec 18.
Diabetes mellitus (DM), poor glycaemic control and raised body mass index (BMI) have been associated with postoperative complications in arthroplasty, although the relative importance of these factors is unclear. We describe the prevalence of DM in elective hip arthroplasty in a UK centre, and evaluate the impact of these factors.
We analysed retrospective data for DM patients undergoing arthroplasty over a 6-year period and compared with non-diabetic matched controls (1 DM patient: 5 controls). DM was present in 5.7% of hip arthroplasty patients (82/1443).
Postoperative complications occurred in 12.2% of DM patients versus 12.9% of controls ( = 1.000); surgical complications were present in 6.1% of those with DM and 2.4% of controls ( = 0.087), while medical complications occurred in 8.5% of DM patients versus 10.7% of controls ( = 0.692). Complications developed in 23.1% of DM patients with poor glycaemic control (HbA1c > 53 mmol/mol) versus 9.8% with good control ( = 0.169). In DM patients and controls combined, complications occurred in 16.3% of obese patients versus 10.0% of non-obese patients ( = 0.043). In the DM cohort, 13.7% of overweight patients had complications versus 0% with a normal or low BMI ( = 0.587).
DM rates were lower than expected, and glycaemic control was good. Overall complication rates were unrelated to the presence of DM or to glycaemic control, although surgical complications were observed more frequently in those with DM and poor glycaemic control was uncommon within our cohort. Complications were more frequent in those with a higher BMI. Whether some patients with DM but without an increased risk of complications are currently being excluded from surgery requires exploration.
糖尿病(DM)、血糖控制不佳和体重指数(BMI)升高与关节置换术后并发症有关,尽管这些因素的相对重要性尚不清楚。我们描述了在英国中心接受髋关节置换术的 DM 患者的患病率,并评估了这些因素的影响。
我们分析了 6 年内接受关节置换术的 DM 患者的回顾性数据,并与非糖尿病匹配对照(1 名 DM 患者:5 名对照)进行比较。在髋关节置换术患者中,DM 的患病率为 5.7%(82/1443)。
DM 患者术后并发症发生率为 12.2%,对照组为 12.9%( = 1.000);DM 患者中有 6.1%发生手术并发症,对照组为 2.4%( = 0.087),而 DM 患者中有 8.5%发生医疗并发症,对照组为 10.7%( = 0.692)。血糖控制不佳(HbA1c>53mmol/mol)的 DM 患者中并发症发生率为 23.1%,血糖控制良好的患者为 9.8%( = 0.169)。在 DM 患者和对照组中,肥胖患者的并发症发生率为 16.3%,非肥胖患者为 10.0%( = 0.043)。在 DM 队列中,超重患者的并发症发生率为 13.7%,而正常或低 BMI 患者的并发症发生率为 0%( = 0.587)。
DM 发生率低于预期,血糖控制良好。总体并发症发生率与 DM 或血糖控制无关,尽管在 DM 患者中观察到更多的手术并发症,且在我们的队列中血糖控制不佳的情况并不常见。并发症在 BMI 较高的患者中更为常见。是否有一些 DM 但无并发症风险增加的患者目前被排除在手术之外,这需要进一步探讨。