宫颈癌放射治疗后引起的圆锥部脊索瘤。
Radiation-induced glioblastoma of the conus medullaris from radiation treatment of cervical cancer.
机构信息
Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines-Manila, Manila, Philippines
Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines-Manila, Manila, Philippines.
出版信息
BMJ Case Rep. 2020 Dec 17;13(12):e238372. doi: 10.1136/bcr-2020-238372.
Radiation-induced spinal glioblastoma is an extremely rare disease with only four previously published reports in the literature. We report the fifth case, a 69-year-old woman who previously underwent treatment with brachytherapy for cervical cancer, and thereafter presented with neurologic deficits from a conus medullaris tumour. Biopsy and histopathology confirm glioblastoma, not otherwise specified. Treatment of spinal glioblastoma consists of surgery, either biopsy or excision and chemoradiation. However, results are still unsatisfactory and prognosis remains poor.
放射性诱导的脊髓胶质母细胞瘤是一种极为罕见的疾病，文献中仅有四起先前的报道。我们报告第五例病例，一名 69 岁女性，先前因宫颈癌接受近距离放射治疗，此后出现脊髓圆锥肿瘤引起的神经功能缺损。活检和组织病理学证实为非典型胶质母细胞瘤。脊髓胶质母细胞瘤的治疗包括手术，即活检或切除和放化疗。然而，结果仍不尽人意，预后仍然较差。
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