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伴有颅内高压和癌性脑膜炎的发作性动眼神经麻痹

Episodic Oculomotor Nerve Palsy with Intracranial Hypertension and Carcinomatous Meningitis.

作者信息

Sahin Turgut, Ozaydın Aksun Zerin, Togay Isikay Canan, Sener Ozden

机构信息

Faculty of Medicine Department of Neurology, Ankara University, Ankara, Turkey.

出版信息

Neuroophthalmology. 2020 May 1;44(6):399-402. doi: 10.1080/01658107.2020.1746815. eCollection 2020.

Abstract

The classically affected cranial nerve from intracranial hypertension is the sixth nerve. Carcinomatous meningitis can cause persistent or progressive cranial nerve palsies by infiltrating them in the subarachnoid space. Here we present a rare case of episodic, short-lasting, and unilateral oculomotor nerve palsy associated with carcinomatous meningitis and intracranial hypertension in a 44-year-old woman diagnosed with metastatic lung adenocarcinoma. As the survival rates enhance for metastatic cancers, neurologists should expect more perplexing neurologic presentations and consider leptomeningeal metastasis and intracranial hypertension in patients who have cancer and present with short episodes of diplopia and unilateral third nerve palsy.

摘要

颅内高压典型累及的脑神经是第六对脑神经。癌性脑膜炎可通过在蛛网膜下腔浸润脑神经而导致持续性或进行性脑神经麻痹。本文报告一例罕见病例,一名44岁诊断为转移性肺腺癌的女性,出现与癌性脑膜炎和颅内高压相关的发作性、短暂性单侧动眼神经麻痹。随着转移性癌症生存率的提高,神经科医生应预期会有更多复杂的神经学表现,并考虑在患有癌症且出现短暂复视和单侧动眼神经麻痹发作的患者中存在柔脑膜转移和颅内高压。

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本文引用的文献

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Pediatr Neurol. 2010 Feb;42(2):141-2. doi: 10.1016/j.pediatrneurol.2009.09.004.
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Episodic third nerve palsy with cryptococcal meningitis.伴有新型隐球菌脑膜炎的发作性动眼神经麻痹
Neurology. 2005 Dec 13;65(11):1845; author reply 1845. doi: 10.1212/01.wnl.0000200032.49563.da.
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Transient oculomotor paralysis in pseudotumor cerebri.
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