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特发性颅外颈内动脉血管痉挛的治疗挑战：病例报告及文献综述

Treatment challenges in idiopathic extracranial ICA vasospasm case report and review of the literature.

作者信息

Graham Edith, Orjuela Karen, Poisson Sharon, Biller Jose

机构信息

Department of Neurology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, United States of America.

Department of Neurology, Neurohospitalist & Stroke Division, University of Colorado, Anschutz Medical Campus, United States of America.

出版信息

eNeurologicalSci. 2020 Dec 6;22:100304. doi: 10.1016/j.ensci.2020.100304. eCollection 2021 Mar.

DOI:10.1016/j.ensci.2020.100304
PMID:33336087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7732996/
Abstract

Idiopathic extracranial internal carotid artery (ICA) vasospasm is a rare pathological phenomenon that may lead to stroke in young patients. We report a case of an 18 year-old female with recurrent extracranial ICA vasospasm since age thirteen. We summarize published data related to this condition including all twenty-three reported cases of extracranial ICA vasospasm. We describe the various proposed pathophysiological mechanisms underlying this disorder. Various treatment modalities have been attempted but there is no known long-term effective treatment.

摘要

特发性颅外颈内动脉血管痉挛是一种罕见的病理现象，可能导致年轻患者中风。我们报告一例18岁女性，自13岁起反复出现颅外颈内动脉血管痉挛。我们总结了与该病症相关的已发表数据，包括所有23例已报告的颅外颈内动脉血管痉挛病例。我们描述了这种疾病潜在的各种病理生理机制。已经尝试了各种治疗方式，但尚无已知的长期有效治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7732996/27e659e6eb51/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7732996/1600da2d9f4c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7732996/27e659e6eb51/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7732996/1600da2d9f4c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6967/7732996/27e659e6eb51/gr2.jpg

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Transl Stroke Res. 2020 Oct;11(5):1041-1051. doi: 10.1007/s12975-020-00779-z. Epub 2020 Jan 23.
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Spontaneous cervical internal carotid artery vasospasm: Case report and literature review.自发性颈内动脉血管痉挛：病例报告及文献综述
Neurol Clin Pract. 2014 Oct;4(5):461-464. doi: 10.1212/CPJ.0000000000000067.
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Recurrent extracranial internal carotid artery vasospasm associated with recreational marijuana use.
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Acta Neurol Belg. 2024 Feb;124(1):359-361. doi: 10.1007/s13760-023-02275-1. Epub 2023 Jul 25.
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Preclinical study for the ameliorating effect of l-ascorbic acid for the oxidative stress of chronic administration of organic nitrates on myocardial tissue in high sucrose/fat rat model.在高蔗糖/高脂肪大鼠模型中，关于L-抗坏血酸对长期给予有机硝酸盐所致心肌组织氧化应激的改善作用的临床前研究。
Saudi Pharm J. 2022 Oct;30(10):1405-1417. doi: 10.1016/j.jsps.2022.07.001. Epub 2022 Jul 19.
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