Sönmezer Murat, Gülümser Çağrı, Sönmezer Meltem, Sükür Yavuz Emre, Atabekoğlu Cem
Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.
Department of Obstetrics and Gynecology, Yuksek Ihtisas University Faculty of Medicine, Ankara, Turkey.
J Obstet Gynaecol Res. 2021 Feb;47(2):800-806. doi: 10.1111/jog.14618. Epub 2020 Dec 17.
To define whether transabdominal ultrasound guided oocyte retrieval (TUGOR) is a feasible, effective and safe method.
A total of 64 patients who underwent TUGOR in a tertiary referral university hospital in vitro fertilization (IVF) clinic were enrolled. Indications, total number of oocytes collected, total number and percentage of mature oocytes, duration of procedure, complication rates and total number of fertilized oocytes were assessed.
The indications for TUGOR were as follows; virgin women with decreased ovarian reserve who opted fertility preservation (n = 52, 81.1%), Ewing Sarcoma (n = 1, 1.56%), breast cancer (n = 4, 6.2%), lymphoma (n = 1, 1.56%) endometrioma (n = 1, 1.56%), immature teratoma of the ovary (n = 1, 1.56%), multiple large uterine fibroids (n = 2, 3.1%), adnexal transposition due to bowel surgery (n = 1, 1.56%) and Mayer Rokitansky Küster Hauser Syndrome (n = 1, 1.56%). Total number of oocytes retrieved and mean number of oocytes collected were 315 and 4.92 ± 1.7 (range 1-21), respectively. The mean duration of the procedure was 12.4 ± 1.2 min. The number and percentage of mature oocytes were 272 and 86.3%, respectively. A total of 14 embryos were frozen in four patients and one blastocyst transfer was performed ending up with live birth. Superficial epigastric artery injury occurred in two patients and resolved spontaneously. No oocyte was retrieved in five patients with single growing follicle in the first attempt.
TUGOR is a feasible, effective and safe method of oocyte retrieval for the purpose of fertility preservation or in patients with inaccessible ovaries via transvaginal route undergoing IVF.
确定经腹超声引导下卵母细胞采集（TUGOR）是否为一种可行、有效且安全的方法。
纳入在一所三级转诊大学医院体外受精（IVF）诊所接受TUGOR的64例患者。评估其适应证、采集的卵母细胞总数、成熟卵母细胞总数及百分比、操作持续时间、并发症发生率和受精的卵母细胞总数。
TUGOR的适应证如下：卵巢储备功能下降的未育女性选择生育力保存（n = 52，81.1%）、尤因肉瘤（n = 1，1.56%）、乳腺癌（n = 4，6.2%）、淋巴瘤（n = 1，1.56%）、子宫内膜瘤（n = 1，1.56%）、卵巢未成熟畸胎瘤（n = 1，1.56%）、多发性大子宫肌瘤（n = 2，3.1%）、因肠道手术导致的附件移位（n = 1，1.56%）和迈耶-罗基坦斯基-库斯特-豪泽综合征（n = 1，1.56%）。采集的卵母细胞总数和平均采集卵母细胞数分别为315个和4.92±1.7个（范围1 - 21个）。操作的平均持续时间为12.4±1.2分钟。成熟卵母细胞的数量和百分比分别为272个和86.3%。4例患者共冷冻14个胚胎，进行了1次囊胚移植，最终分娩活婴。2例患者发生腹壁浅动脉损伤，自行缓解。首次尝试时，5例仅有单个生长卵泡的患者未采集到卵母细胞。
TUGOR是一种可行、有效且安全的卵母细胞采集方法，可用于生育力保存或经阴道途径无法触及卵巢的IVF患者。
