Department of Ophthalmology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
Eur Rev Med Pharmacol Sci. 2020 Dec;24(23):12009-12015. doi: 10.26355/eurrev_202012_23989.
To investigate the effects of orthokeratology on biological parameters and visual quality of adolescents with low-grade corneal astigmatism myopia.
In this study, a total of 41 myopic adolescents were prescribed with orthokeratology glasses in our hospital from February 2018 to March 2019 and voluntarily cooperated with relevant examinations before and after wearing orthokeratology lenses. Patients' uncorrected distant visual acuity (UCVA-D), uncorrected near visual acuity (UCVA-N) and naked eye near stereoacuity before wearing glasses, 1 month, and 3 months after wearing glasses were observed. The corneal astigmatism of patients was observed. The corneal endothelial cell density was observed. The dynamic adjustment function (NP, AF, NRA, PRA) values of patients were observed. The comparison of biological indexes in different time periods was observed. The changes of corneal curvature before wearing orthokeratology lens, 1 month and 3 months after wearing orthokeratology lens were observed.
There were significant changes of patients 1 month after wearing orthokeratology lenses (p < 0.05), while there was no significant difference between 3 months after wearing the orthokeratology lenses and 1 month after wearing the orthokeratology lenses (p < 0.05). Patients' NCAV-D and UCVA-N were recorded by a conversion method of 5 points. There were differences in the NCVA-D, NCVA-N, naked eye near stereoacuity before, 1 month, and 3 months after wearing glasses (p < 0.05). By observing patients' biological indicators and dynamic adjustment, it was found that there were statistically significant differences in NP, AF, BRA and PRA before wearing the glasses, 1 month and 3 months after wearing the glasses (p < 0.05).
The use of orthokeratology can greatly correct myopia patients' vision, improve their stereoscopic vision, control the progression of myopia, and improve their eye regulation, which is of high safety and great short-term effect.
研究角膜塑形术对低度角膜散光性近视青少年生物学参数和视觉质量的影响。
本研究共选取我院 2018 年 2 月至 2019 年 3 月收治的 41 例近视青少年，均采用角膜塑形镜矫正，自愿配合相关检查，在戴镜前后分别观察患者的未矫正远视力（UCVA-D）、未矫正近视力（UCVA-N）和裸眼近立体视，观察患者的角膜散光，观察角膜内皮细胞密度，观察患者的动态调节功能（NP、AF、NRA、PRA）值，观察不同时间点的生物学指标，观察佩戴角膜塑形镜前、佩戴角膜塑形镜 1 个月和 3 个月后角膜曲率的变化。
患者佩戴角膜塑形镜 1 个月后有明显变化（p<0.05），而佩戴角膜塑形镜 3 个月后与佩戴角膜塑形镜 1 个月后相比无明显差异（p<0.05）。患者的 NCAV-D 和 UCVA-N 采用 5 分制换算法记录，在戴镜前、戴镜 1 个月、戴镜 3 个月后 NCVA-D、NCVA-N、裸眼近立体视的差异均有统计学意义（p<0.05）。通过观察患者的生物学指标和动态调节，发现戴镜前、戴镜 1 个月、戴镜 3 个月时 NP、AF、BRA 和 PRA 差异均有统计学意义（p<0.05）。
角膜塑形术的应用能较大程度地矫正近视患者的视力，提高其立体视觉，控制近视进展，改善其眼调节功能，安全性高，短期效果显著。
