Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
J Neonatal Perinatal Med. 2021;14(3):419-426. doi: 10.3233/NPM-200508.
Timely delivery and magnesium sulfate (MgSO4) are mainstay in the treatment of preeclampsia with severe features (PWSF). Premature delivery, severity of illness and mother-infant separation may increase the risk for breastfeeding (BF) initiation failure.
To compare BF initiation among women with late-onset PWSF treated with MgSO4 to women with late-onset preeclampsia without severe features (WOSF) who did not receive MgSO4.
Retrospective study of 158 women with PWSF and 104 with WOSF who delivered at ≥34 weeks. Intention to BF, formula feed (FF) or partially BF was declared prenatally. At discharge, exclusive BF included direct BF or direct BF with expressed breast milk (EBM).
PWSF and WOSF groups were similar in age, race, and obstetric history. PWSF and WSOF differed in primiparity (65 & 51%), late preterm births (73 vs 15%), admission to NICU (44 &17%) and mother (5 & 4d) and infant (6 & 3d) hospital stay. Both groups were similar in intention to BF (80 & 84%), to FF (16 & 13%) and to partially BF (5 & 5%). At discharge, exclusive BF (37 & 39%), partial BF (33 & 31%) and FF (30 & 30%) were similar. Exclusive BF in the PWSF group was 43% direct BF, 28% direct BF and EBM and 29% EBM alone whereas in the WOSF group exclusive BF was 93% direct BF and 7% direct BF and EBM.
BF initiation rates for women with PWSF and WOSF were similar. EBM alone or with direct BF enabled infants in the PWSF group to exclusively BF at discharge.
及时分娩和硫酸镁(MgSO4)是治疗重度子痫前期(PWSF)的主要方法。早产、疾病严重程度和母婴分离可能会增加母乳喂养(BF)启动失败的风险。
比较接受硫酸镁治疗的晚发型重度子痫前期(PWSF)与未接受硫酸镁治疗的晚发型无重度特征子痫前期(WOSF)妇女的 BF 启动情况。
回顾性研究了 158 例 PWSF 患者和 104 例 WOSF 患者,分娩时孕周均≥34 周。产前声明 BF 意向、配方奶(FF)或部分 BF。出院时,纯 BF 包括直接 BF 或直接 BF 加母乳(EBM)。
PWSF 和 WOSF 组在年龄、种族和产科史方面相似。PWSF 和 WSOF 在初产妇(65%和 51%)、晚期早产儿(73%和 15%)、新生儿重症监护病房(NICU)入院(44%和 17%)和母婴(5%和 4d)及婴儿(6%和 3d)住院时间方面存在差异。两组在 BF 意向(80%和 84%)、FF(16%和 13%)和部分 BF(5%和 5%)方面相似。出院时,纯 BF(37%和 39%)、部分 BF(33%和 31%)和 FF(30%和 30%)相似。PWSF 组纯 BF 中直接 BF 占 43%,直接 BF 和 EBM 占 28%,EBM 单独占 29%;而 WOSF 组纯 BF 中直接 BF 占 93%,直接 BF 和 EBM 占 7%。
PWSF 和 WOSF 妇女的 BF 启动率相似。EBM 单独或与直接 BF 使 PWSF 组的婴儿在出院时能够纯 BF。