Department of Pediatrics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
J Neonatal Perinatal Med. 2021;14(3):427-432. doi: 10.3233/NPM-200534.
Knowledge on short-term outcomes of preterm infants is important for quality control. Our objective was to analyze the outcomes of very low birth weight infants admitted to our neonatal intensive care unit over a ten years' period and to compare the results with internationally published data.
We analyzed the outcome measures for all live born infants with birth weight (BW) of 400-1500 grams and gestational age (GA) of 23-32 weeks born at King Faisal Specialist Hospital & Research Centre between 2006 and 2015. Results were compared to data from four international neonatal networks.
During the study period, we admitted 528 infants born at a gestational age of≥23 and≤32 weeks with a very low birth weight (VLBW) of 400-1500 grams. Mean (SD) GA was 28 (2.4) weeks and mean (SD) BW was 1007 (290) grams. A hundred and twenty-nine (24.4%) infants were small for gestational age and major congenital anomalies were present in 56 (10.6 %) infants. The rate of bronchopulmonary dysplasia (BPD) was 24.4 %, necrotizing enterocolitis (NEC) 9.1%, patent ductus arteriosus (PDA) 29.9%, severe intraventricular hemorrhage (IVH)10.8 %, periventricular leukomalacia (PVL) 5.7%, severe retinopathy of prematurity (ROP) 8%, and late-onset sepsis was 18.8%. The incidences of major neonatal outcomes such as CLD, NEC, severe IVH and severe ROP were comparable to the international cohorts.
In our population of preterm infants, survival rates and complications of prematurity were comparable to international data.
了解早产儿的短期预后结果对于质量控制非常重要。我们的目的是分析在过去十年中我院新生儿重症监护病房收治的极低出生体重儿的结局，并与国际上发表的数据进行比较。
我们分析了 2006 年至 2015 年在法赫德国王专科医院和研究中心出生、出生体重为 400-1500 克、胎龄为 23-32 周的所有活产儿的结局指标。结果与来自四个国际新生儿网络的数据进行了比较。
在研究期间，我们收治了 528 名胎龄≥23 周且≤32 周、出生体重为 400-1500 克的极低出生体重儿（VLBW）。平均（标准差）胎龄为 28（2.4）周，平均（标准差）出生体重为 1007（290）克。129 名（24.4%）婴儿为小于胎龄儿，56 名（10.6%）婴儿存在重大先天性畸形。支气管肺发育不良（BPD）的发生率为 24.4%，坏死性小肠结肠炎（NEC）为 9.1%，动脉导管未闭（PDA）为 29.9%，严重脑室出血（IVH）为 10.8%，脑室周围白质软化（PVL）为 5.7%，严重早产儿视网膜病变（ROP）为 8%，晚发性败血症为 18.8%。CLD、NEC、严重 IVH 和严重 ROP 等主要新生儿结局的发生率与国际队列相当。
在我们的早产儿人群中，生存率和早产并发症与国际数据相当。
