Department No 16 of Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Department of Plastic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Aesthet Surg J. 2021 Oct 15;41(11):NP1686-NP1694. doi: 10.1093/asj/sjaa385.
Many techniques and devices have been developed to improve small volume fat grafting efficiency and consistency for use in the operating room and outpatient procedure room. These methods require cumbersome or messy processing to remove excess oil and fluid from adipose graft.
The aim of this study was to compare the fat processing efficiency of a novel handheld device, the Push-to-Spin (P2S) system, with that of other common processing techniques and validate tissue quality after lipoaspirate processing.
Human lipoaspirate samples were processed by 1 of 3 methods: cotton gauze (Telfa) rolling, centrifugation (Coleman technique), or the P2S system. Efficiency of fat processing was evaluated in terms of total processing time, fat harvest ratio, and fat processed ratio. Histologic examination and immunohistochemical staining were used to compare tissue morphology and adipocyte viability, respectively. Experimental samples were compared with unprocessed lipoaspirate controls.
Lipoaspirate processing was significantly faster with the P2S device than with other techniques. All 3 methods achieved similar fat harvest and fat processing ratios. Additionally, the P2S, Telfa, and Coleman techniques yielded grafts with similar cellularity and with similar perilipin and glycerol-3-phosphate dehydrogenase 1 expression. Measured differences between experimental and control samples were statistically significant.
The P2S device is an easy-to-use, efficient, and potentially cost-effective handheld device that can be used for lipoaspirate harvest, processing, and grafting in any procedural setting. The resulting adipocytes have similar morphology, viability, and function to those yielded by other techniques. This handheld technology decreases procedure time, thereby improving surgeon efficiency and patient experience.
为了提高小体积脂肪移植的效率和一致性，已经开发出许多技术和设备，可用于手术室和门诊手术。这些方法需要繁琐或混乱的处理过程，以从脂肪移植物中去除多余的油和液体。
本研究旨在比较新型手持设备 Push-to-Spin（P2S）系统与其他常见处理技术的脂肪处理效率，并验证脂肪抽吸处理后的组织质量。
用人脂肪抽吸样本通过 1 种方法进行处理：棉花纱布（Telfa）滚动、离心（Coleman 技术）或 P2S 系统。以总处理时间、脂肪收获比和脂肪处理比评估脂肪处理效率。组织学检查和免疫组织化学染色分别用于比较组织形态和脂肪细胞活力。实验样本与未经处理的脂肪抽吸对照物进行比较。
与其他技术相比，P2S 设备处理脂肪抽吸的速度明显更快。所有 3 种方法均实现了相似的脂肪收获和脂肪处理比例。此外，P2S、Telfa 和 Coleman 技术产生的移植物具有相似的细胞密度，以及相似的甘油三酯和甘油磷酸脱氢酶 1 的表达。实验样本与对照样本之间的差异具有统计学意义。
P2S 设备是一种易于使用、高效且具有潜在成本效益的手持式设备，可用于任何手术环境中的脂肪抽吸、处理和移植。所产生的脂肪细胞具有与其他技术相似的形态、活力和功能。这种手持式技术可缩短手术时间，从而提高手术医生的效率和患者体验。
