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新冠疫情期间中国孕妇及产后女性的抑郁症状发生率。

Prevalence of Depressive Symptoms Among Pregnant and Postpartum Women in China During the COVID-19 Pandemic.

机构信息

From the Department of Nursing (Bo), Peking Union Medical College Hospital, Beijing; Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences (Yang, Xiang), University of Macau; Center for Cognition and Brain Sciences (Yang, Xiang), University of Macau, Macao SAR; Department of Psychiatry (Yang), Southern Medical University Nanfang Hospital, Guangdong; Department of Gynaecology and Obstetrics (Chen, M. Zhang, D.Y. Zhang, Y. Li, Y. Li, R. Li), Peking Union Medical College Hospital, Beijing; School of Nursing (Cheung), Hong Kong Polytechnic University, Hong Kong SAR, China; and Department of Psychiatry (Ng), The Melbourne Clinic and St Vincent's Hospital, University of Melbourne, Richmond, Victoria, Australia.

出版信息

Psychosom Med. 2021 May 1;83(4):345-350. doi: 10.1097/PSY.0000000000000904.

Abstract

OBJECTIVE

According to recent studies, the COVID-19 pandemic has been associated with an increased risk of mental health problems across many subpopulations including pregnant and postnatal women. This study examined the prevalence and correlates of depressive symptoms (depression hereafter) in Chinese pregnant and postpartum women during the COVID-19 pandemic.

METHODS

This was a multicenter, cross-sectional study comprising 1309 pregnant and postpartum women across 12 provinces in China during the COVID-19 pandemic. Depression was assessed using the nine-item Patient Health Questionnaire. Univariate analyses and multivariate logistic regression analyses were conducted.

RESULTS

The prevalence of depression in pregnant and postpartum women was 27.43% (95% confidence interval [CI] = 25.01%-29.85%). Women who were worried about themselves or their babies being infected with COVID-19 (odds ratio [OR] = 2.562, 95% CI = 1.670-3.929), and those who had delayed regular medical checkups (OR = 2.434, 95% CI = 1.580-3.750) were at higher risk of depression. Compared with those living in central and western parts of China, women living in northern (OR = 0.513, 95% CI = 0.326-0.807) and southeastern parts of China (OR = 0.626, 95% CI = 0.463-0.846) were less likely to have depression.

CONCLUSIONS

The COVID-19 pandemic was associated with an increased likelihood of mental health problems among pregnant and postnatal women. Over a quarter of the pregnant and postpartum women in China had depression during the COVID-19 pandemic. Considering the negative health impact of depression, preventive measures, regular mental health screening, and medical checkups are needed with the goal to reduce the risk of depression in this vulnerable population during a pandemic.

摘要

目的

根据最近的研究,COVID-19 大流行使许多亚人群(包括孕妇和产后妇女)的心理健康问题风险增加。本研究调查了 COVID-19 大流行期间中国孕妇和产后妇女抑郁症状(以下简称抑郁)的患病率及其相关因素。

方法

这是一项多中心、横断面研究,纳入了 COVID-19 大流行期间中国 12 个省份的 1309 名孕妇和产后妇女。使用 9 项患者健康问卷评估抑郁。进行了单因素分析和多因素逻辑回归分析。

结果

孕妇和产后妇女的抑郁患病率为 27.43%(95%置信区间[CI] = 25.01%-29.85%)。担心自己或婴儿感染 COVID-19(比值比[OR] = 2.562,95%CI = 1.670-3.929)以及延迟定期产检(OR = 2.434,95%CI = 1.580-3.750)的女性患抑郁的风险更高。与居住在中国中西部地区的女性相比,居住在中国北部(OR = 0.513,95%CI = 0.326-0.807)和东南部地区(OR = 0.626,95%CI = 0.463-0.846)的女性发生抑郁的可能性较低。

结论

COVID-19 大流行与孕妇和产后妇女心理健康问题的发生风险增加有关。在中国,超过四分之一的孕妇和产后妇女在 COVID-19 大流行期间患有抑郁。考虑到抑郁对健康的负面影响,需要采取预防措施、定期进行心理健康筛查和产检,以降低这一脆弱人群在大流行期间发生抑郁的风险。

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