Division of Rehabilitation Science (Drs Keller-Ross and Gillick and Mr Chantigian) and Division of Physical Therapy (Drs Keller-Ross, Nemanich, and Gillick), Department of Rehabilitation, Medical School, University of Minnesota, Minneapolis, Minnesota.
Pediatr Phys Ther. 2021 Jan 1;33(1):11-16. doi: 10.1097/PEP.0000000000000762.
To determine the influence of combined transcranial direct current stimulation (tDCS) to the motor cortex (M1) and bimanual training on cardiovascular function in children with cerebral palsy (CP).
Mean arterial pressure (MAP), heart rate (HR), and HR variability (HRV) were measured immediately before and after 20 minutes of cathodal tDCS to contralesional M1 and bimanual training on days 1, 6, and 10 of a 10-day trial in 8 participants (5 females, 7-19 years).
Baseline MAP and HR were similar across days (93 ± 10 mm Hg and 90 ± 10 bpm, P > .05). MAP was similar from baseline to postintervention across all 3 days. Systolic pressure, diastolic pressure, nor HR significantly changed. HRV was not influenced by the 10-day intervention.
Combined cathodal tDCS to M1 and bimanual training does not influence autonomic and cardiovascular function in children with CP due to perinatal stroke.
研究经颅直流电刺激(tDCS)联合双手训练对脑卒中后脑瘫儿童心血管功能的影响。
8 名参与者(5 名女性,7-19 岁)连续 10 天,每天进行 1 次对侧大脑运动皮质(M1)的阴极 tDCS 和双手训练,共 20 分钟。分别于第 1、6、10 天治疗前和治疗后即刻测量平均动脉压(MAP)、心率(HR)和心率变异性(HRV)。
3 天的基础 MAP 和 HR 相似(93±10mmHg 和 90±10bpm,P>.05)。所有 3 天的 MAP 从基线到干预后均无显著差异。收缩压、舒张压和 HR 均无显著变化。HRV 也不受 10 天干预的影响。
经颅直流电刺激联合双手训练对脑卒中后脑瘫儿童的自主神经和心血管功能没有影响。