Medicine Service, VA Medical Center, Birmingham, AL; Department of Medicine at School of Medicine, and Division of Epidemiology at School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Clin Exp Rheumatol. 2021 Mar-Apr;39 Suppl 129(2):56-61. doi: 10.55563/clinexprheumatol/ammhi6. Epub 2020 Dec 2.
To assess the top 5 causes of non-vasculitis hospitalisations in people with vasculitis over time.
In a national U.S. sample of people with vasculitis hospitalised for reasons other than vasculitis, the rank (and percent) of top 5 causes of hospitalisations and in-hospital mortality were compared in 1998-99 versus 2013-2014.
The top 5 ranked disease categories responsible for non-vasculitis hospitalisations in people with vasculitis in 1998-99 versus 2013-14 were as follows, respectively: (#1) circulatory system disease versus the same; (#2) heart disease versus infections/parasitic diseases; (#3) digestive system disease versus bacterial infection; (#4) respiratory disease versus septicaemia; and (#5) musculoskeletal disease versus unspecified septicaemia. The respective top 5 CCS category ranks for in-hospital mortality in people with vasculitis in 1998-1999 versus 2013-2014 were: (#1) respiratory disease versus infections/parasitic diseases; (#2) circulatory system disease versus bacterial infection; (#3) heart disease versus septicaemia; (#4) respiratory infection versus unspecified septicaemia; and (#5) pneumonia versus circulatory system disease.
Infections replaced cardio-pulmonary disease among the top 5 causes for non-primary vasculitis hospitalisations and associated in-hospital mortality in people with vasculitis over time. Studies should examine modifiable factors associated with infection in vasculitis and design interventions to reduce this burden.
评估随时间推移，血管炎患者非血管炎住院的前 5 大病因。
在美国，对因非血管炎住院的血管炎患者进行了全国性抽样调查，比较了 1998-99 年与 2013-2014 年，导致住院和院内死亡的前 5 大病因的排名（和百分比）。
1998-99 年与 2013-14 年，血管炎患者非血管炎住院的前 5 大疾病类别分别为：（#1）循环系统疾病与相同类别；（#2）心脏病与感染/寄生虫病；（#3）消化系统疾病与细菌感染；（#4）呼吸道疾病与败血症；以及（#5）肌肉骨骼疾病与未特指的败血症。1998-1999 年与 2013-2014 年，血管炎患者院内死亡的前 5 大 CCS 类别分别为：（#1）呼吸道疾病与感染/寄生虫病；（#2）循环系统疾病与细菌感染；（#3）心脏病与败血症；（#4）呼吸道感染与未特指的败血症；以及（#5）肺炎与循环系统疾病。
随着时间的推移，感染取代了心肺疾病，成为血管炎患者非原发性血管炎住院及相关院内死亡的前 5 大病因之一。研究应检查与血管炎感染相关的可改变因素，并设计干预措施来减轻这一负担。
