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《维生素D补充对人体IGF-1水平的影响:一项系统评价与荟萃分析》中效应量的重复计算及对研究的不当排除

Double-counting of effect sizes and inappropriate exclusion of studies in "The influence of vitamin D supplementation on IGF-1 levels in humans: A systematic review and meta-analysis".

作者信息

Amiri Mojgan, Raeisi-Dehkordi Hamidreza, Vorland Colby J, Chen Xiwei, Brown Andrew W, Allison David B

机构信息

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Ageing Res Rev. 2021 Mar;66:101236. doi: 10.1016/j.arr.2020.101236. Epub 2020 Dec 15.

Abstract

We read with interest the review by Kord-Varkaneh et al. which examined the effects of vitamin D supplementation on IGF-1 levels in humans. We believe that the article suffers from severe methodological faults and subsequently the conclusions are likely to be biased. Thus, the authors should address the mentioned limitations and update the analyses to provide robust and trustful estimates. We are concerned that without correction, the analyses may lead to erroneous findings and conclusions.

摘要

我们饶有兴趣地阅读了科尔德 - 瓦尔卡内等人的综述,该综述探讨了补充维生素D对人体胰岛素样生长因子 - 1(IGF - 1)水平的影响。我们认为这篇文章存在严重的方法学缺陷,因此其结论可能存在偏差。因此,作者应解决上述局限性并更新分析,以提供可靠且可信的估计。我们担心如果不进行修正,这些分析可能会导致错误的发现和结论。

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