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约旦安曼国家血库献血者中输血传播感染与ABO和Rh血型的患病率及相关性

Prevalence and Association of Transfusion Transmitted Infections with ABO and Rh Blood Groups among Blood Donors at the National Blood Bank, Amman, Jordan.

作者信息

Hroob Amir M Al, Saghir Sultan A M, Almaiman Amer A, Alsalahi Omar S A, Al-Wajeeh Abdullah S, Al-Shargi Omar Y A, Al-Balagi Nader, Mahmoud Ayman M

机构信息

Department of Medical Analysis, Princess Aisha Bint Al-Hussein College of Nursing and Medical Sciences, Al-Hussein Bin Talal University, Ma'an 71111, Jordan.

Department of Applied Medical Sciences, Community College of Unaizah, Qassim University, Buraydah 51431, Saudi Arabia.

出版信息

Medicina (Kaunas). 2020 Dec 16;56(12):701. doi: 10.3390/medicina56120701.

Abstract

Blood screening is considered a compulsory procedure in health care services to reduce the occurrence of transfusion transmitted infections (TTIs). This study estimated the distribution rates of ABO and Rh blood group systems, prevalence rates of TTIs among blood donors and their association with the ABO blood group and Rh system. A retrospective study was conducted at the national blood bank, Amman, Jordan for a period of 6 years (from January 2013 to December 2018). For TTIs analysis, about 5 mL blood sample was collected from each volunteer. A total of 365,029 persons (346,048 (94.8%) males and 18,981 (5.2%) females) donated their blood at the national blood bank, Amman, Jordan from January 2013 to December 2018. The results revealed that O and A were the most prevalent blood groups (37.44% and 36.82%, respectively), followed by B (18.62%) and AB (7.12%). The distribution of Rh + ve and Rh - ve among blood donors showed that Rh + ve donors were more prevalent (88.73%) compared with Rh - ve (11.27%). HBsAg was the most prevalent viral infection (0.38%) followed by HCV (0.13%), syphilis (0.02%), HIV (0.006%) and the male donors were highly infected when compared with female donors. The association between ABO/Rh blood groups and TTIs infections was nonsignificant. In conclusion, low frequency rates of TTIs among blood donors were detected in the current study, but improvements are still continuously required. Low percentages of female donors need to be managed via conducting health cultural education programs.

摘要

在医疗保健服务中,血液筛查被视为一项强制性程序,以减少输血传播感染(TTIs)的发生。本研究估计了ABO和Rh血型系统的分布率、献血者中TTIs的流行率及其与ABO血型和Rh系统的关联。在约旦安曼的国家血库进行了一项为期6年(从2013年1月至2018年12月)的回顾性研究。对于TTIs分析,从每位志愿者采集约5毫升血液样本。2013年1月至2018年12月期间,共有365,029人(346,048人(94.8%)为男性,18,981人(5.2%)为女性)在约旦安曼的国家血库献血。结果显示,O型和A型是最常见的血型(分别为37.44%和36.82%),其次是B型(18.62%)和AB型(7.12%)。献血者中Rh阳性和Rh阴性的分布表明,Rh阳性献血者比Rh阴性献血者更普遍(分别为88.73%和11.27%)。HBsAg是最常见的病毒感染(0.38%),其次是HCV(0.13%)、梅毒(0.02%)、HIV(0.006%),与女性献血者相比,男性献血者感染率更高。ABO/Rh血型与TTIs感染之间的关联不显著。总之,本研究检测到献血者中TTIs的发生率较低,但仍需要持续改进。需要通过开展健康文化教育项目来管理女性献血者比例较低的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cdc/7765551/bd639b77b4be/medicina-56-00701-g001.jpg

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