通过深度学习技术减少儿科 Tc-DMSA SPECT 的扫描时间。
Reducing scan time of paediatric Tc-DMSA SPECT via deep learning.
机构信息
Department of Nuclear Medicine, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Gueishan Dist., Taoyuan, 33305, Taiwan.
Department of Nuclear Medicine, Chang Gung Memorial Hospital, No. 5, Fuxing Street, Gueishan Dist., Taoyuan, 33305, Taiwan; Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, No. 259, Wenhua 1st Rd., Guishan Dist., Taoyuan, 33302, Taiwan.
出版信息
Clin Radiol. 2021 Apr;76(4):315.e13-315.e20. doi: 10.1016/j.crad.2020.11.114. Epub 2020 Dec 16.
AIM
To investigate the feasibility of reducing the scan time of paediatric technetium 99m (Tc) dimercaptosuccinic acid (DMSA) single-photon-emission computed tomographic (SPECT) using a deep learning (DL) method.
MATERIAL AND METHODS
A total of 112 paediatric Tc-DMSA renal SPECT scans were analysed retrospectively. Of the 112 examinations, 88 (84 for training and four for validation) were used to train a DL-based model that could generate full-acquisition-time reconstructed SPECT images from half-time acquisition. The remaining 24 examinations were used to evaluate the performance of the trained model.
RESULTS
DL-based SPECT images obtained from half-time acquisition have image quality similar to the standard clinical SPECT images obtained from full-acquisition-time acquisition. Moreover, the accuracy, sensitivity and specificity of the DL-based SPECT images for detection of affected kidneys were 91.7%, 83.3%, and 100%, respectively.
CONCLUSION
These preliminary results suggest that DL has the potential to reduce the scan time of paediatric Tc-DMSA SPECT imaging while maintaining diagnostic accuracy.
目的
探讨使用深度学习（DL）方法降低儿童锝 99m（Tc）二巯丁二酸（DMSA）单光子发射计算机断层扫描（SPECT）扫描时间的可行性。
材料与方法
回顾性分析了 112 例儿童 Tc-DMSA 肾 SPECT 扫描。112 项检查中，88 项（84 项用于训练，4 项用于验证）用于训练基于 DL 的模型，该模型可从半时间采集生成全采集时间重建的 SPECT 图像。其余 24 项检查用于评估训练模型的性能。
结果
从半时间采集获得的基于 DL 的 SPECT 图像的图像质量与从全采集时间采集获得的标准临床 SPECT 图像相似。此外，基于 DL 的 SPECT 图像检测受影响肾脏的准确性、敏感性和特异性分别为 91.7%、83.3%和 100%。
结论
这些初步结果表明，DL 有可能在保持诊断准确性的同时，降低儿童 Tc-DMSA SPECT 成像的扫描时间。
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