Artificial intelligence (AI) is a subdiscipline of computer science that has made substantial progress in medicine and there is a growing body of AI research in dentistry. Dentists should have an understanding of the foundational concepts and the ability to critically evaluate dental research in AI. Machine learning (ML) is a subfield of AI that most dental AI research is dedicated to. The most prolific area of ML research is automated interpretation of dental imaging. Other areas include providing treatment recommendations, predicting future disease and treatment outcomes. The research impact is limited by small datasets that do not harness the positive correlation between very large datasets and ML performance. There is also a need to standardize research methodologies and utilize performance metrics that are appropriate for the clinical context. In addition to research challenges, this article discusses the ethical, legal and logistical considerations associated with implementation in clinical practice. This includes explainable AI, model bias, data privacy and security. The future implications of AI in dentistry involve a promise for a novel form of practicing dentistry however, the effect of AI on patient outcomes is yet to be determined.