Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Head Neck. 2021 Apr;43(4):1202-1212. doi: 10.1002/hed.26580. Epub 2020 Dec 19.
Benign connective and soft-tissue neoplasms (CSTNs) are unusual in the head and neck region. The aim of the present study was to evaluate the demographic and clinicopathological features of these neoplasms.
A cross-sectional study was conducted of cases diagnosed as benign CSTNs, with data collected from biopsy records. The chi-square test was used. A p-value <0.05 was considered indicative of statistical significance.
Among the 38 119 specimens, 1066 (2.79%) were benign CSTNs: 369 fibroblastic/myofibroblastic, 250 adipocytic, 179 vascular, 130 neural, 94 osseous/cartilaginous, 19 muscular, and two fibrohistiocytic. Most patients were female (62.8%) and white-skinned (45.8%). Mean age was 42 years. The tongue (25.2%) was the most affected site for extraosseous neoplasms.
This study had the largest sample of benign oral and maxillofacial CSTNs. Although these tumors have similar clinical features, the characterization and differentiation detailed here may help clinicians with regards to the correct diagnosis.
头颈部良性结缔组织和软组织肿瘤（CSTN）较为少见。本研究旨在评估这些肿瘤的人口统计学和临床病理特征。
对经活检诊断为良性 CSTN 的病例进行了横断面研究，收集了活检记录中的数据。采用卡方检验。p 值<0.05 被认为具有统计学意义。
在 38119 份标本中，有 1066 份（2.79%）为良性 CSTN：369 份成纤维细胞/肌纤维母细胞性、250 份脂肪性、179 份血管性、130 份神经源性、94 份骨/软骨源性、19 份肌肉源性和 2 份纤维组织细胞性。大多数患者为女性（62.8%）和白种人（45.8%）。平均年龄为 42 岁。对于骨外肿瘤，最常受累的部位是舌（25.2%）。
本研究的良性口腔颌面部 CSTN 样本量最大。尽管这些肿瘤具有相似的临床特征，但此处详细的特征描述和鉴别有助于临床医生做出正确诊断。
