Department of Psychiatry, Dankook University Hospital, Cheonan, Korea; Department of Psychiatry, Dankook University College of Medicine, Cheonan, Korea.
Environmental Health Center, Dankook University Medical Center, Cheonan, Korea; Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea.
J Affect Disord. 2021 Feb 15;281:256-263. doi: 10.1016/j.jad.2020.12.002. Epub 2020 Dec 5.
Depressive disorders have various symptom presentations, which may have complex and dynamic interactions. This study aimed to investigate the network structures underlying the symptoms and to identify the central symptoms of depression in school-aged children.
Participants were a large community sample of elementary school children aged 6 to 12 years (N = 10,233). To assess the depressive symptoms, we utilized the Children's Depression Inventory (CDI). We binarized the scores on the CDI to generate a symptom network using the eLasso method, based on the Ising model. We evaluated the centralities in individual symptoms using the network centrality indices and the associations between symptoms.
Of the symptoms, loneliness, self-hatred, school dislike, and low self-esteem were the most central symptoms in the network of depressive symptoms. School work difficulty-school performance decrement, sadness-crying, self-hatred-negative body image, low self-esteem-fight, anhedonia-school dislike, sadness-loneliness, self-deprecation-school work difficulty, and school dislike-lack of friendship had significantly higher edge weight than most edges. The estimated network between the symptoms was robust to stability and accuracy tests.
Participants were not clinical but community samples, who show lower level of symptoms.
The present symptom network analysis provided important insights on various interconnectivities between individual symptoms in childhood depression and on the central symptoms. In addition, our findings presented both similarities and differences with a previous Western study, thus, warranting future cross-cultural studies.
抑郁障碍有多种症状表现,这些症状可能存在复杂而动态的相互作用。本研究旨在探究儿童抑郁障碍症状的网络结构,并确定其核心症状。
参与者为年龄在 6 至 12 岁的小学儿童的大型社区样本(N=10233)。我们采用儿童抑郁量表(CDI)评估抑郁症状。我们基于伊辛模型,采用 eLasso 方法对 CDI 评分进行二值化,以生成症状网络。我们采用网络中心度指标和症状间的关联评估个体症状的中心度。
在抑郁症状网络中,孤独、自我憎恶、讨厌上学和自卑是最核心的症状。学业困难-学业成绩下降、悲伤-哭泣、自我憎恶-负面身体意象、自卑-打架、快感缺失-讨厌上学、悲伤-孤独、自我贬低-学业困难以及讨厌上学-缺乏友谊这些症状之间的联系比大多数症状之间的联系更紧密。症状之间的估计网络在稳定性和准确性测试中是稳健的。
参与者为社区样本而非临床样本,他们的症状水平较低。
本研究采用症状网络分析方法,深入探讨了儿童抑郁障碍中各症状之间的复杂相互关系以及核心症状。此外,我们的研究结果与之前的西方研究既有相似之处,也有不同之处,因此值得开展进一步的跨文化研究。