[淋巴上皮瘤样肝癌：现状与进展]

[Lymphoepithelioma-like hepatic carcinoma: the current status and progress].

作者信息

Tao C C, Zhang K, Rong W Q, Wu J X

机构信息

Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2020 Dec 23;42(12):996-1000. doi: 10.3760/cma.j.cn112152-20200114-00036.

DOI:10.3760/cma.j.cn112152-20200114-00036

PMID:33342154

Abstract

Lymphoepithelioma-like hepatic carcinoma (LELC) is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, characterized by dense lymphocyte infiltration.It can be divided into lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) and lymphoepithelioma-like cholangiocarcinoma (LEL-CC). The diagnosis is mainly based on pathology, and the treatment is mainly surgery. The prognosis of LELC is good, which may be related to a large number of lymphocyte infiltration. The data of LELC is very limited, only a few case reports and small retrospective studies, which needs further exploration and research. Up to now, 67 cases of LEL-HCC and 34 cases of LEL-CC have been reported. The purpose of this review is to provide a comprehensive overview of the current research situation on LELC in terms of epidemiology, clinical treatment, pathology and research prospects.

摘要

淋巴上皮瘤样肝癌（LELC）是一种罕见的具有独特流行病学和病理特征的肝癌特殊变体，其特征为密集的淋巴细胞浸润。它可分为淋巴上皮瘤样肝细胞癌（LEL-HCC）和淋巴上皮瘤样胆管癌（LEL-CC）。诊断主要基于病理，治疗主要是手术。LELC的预后良好，这可能与大量淋巴细胞浸润有关。关于LELC的数据非常有限，仅有少数病例报告和小型回顾性研究，这需要进一步探索和研究。截至目前，已报道67例LEL-HCC和34例LEL-CC。本综述的目的是从流行病学、临床治疗、病理及研究前景等方面对LELC的当前研究状况进行全面概述。