University of California Riverside School of Medicine, Riverside, CA.
Dermatol Online J. 2020 Nov 15;26(11):13030/qt1d9925s0.
Mastocytosis is a rare condition in which mast cells accumulate throughout various organs of the body-the most common subtype being confined to the skin. We present an unusual case of cutaneous mastocytosis localized to the unilateral breast of a young woman with partial involvement of the areola. Previously diagnosed as nipple eczema, the patient failed appropriate treatment with class III and IV topical corticosteroids. Given it was adult onset, failed appropriate treatment, and had an atypical clinical appearance, a biopsy was pursued that revealed mastocytosis in skin. This is another clinical diagnosis dermatologists may consider in their differential diagnosis of nipple dermatitis.
肥大细胞增多症是一种罕见的疾病，其中肥大细胞在身体的各种器官中积累 - 最常见的亚型局限于皮肤。我们提出了一个不寻常的病例，即一名年轻女性单侧乳房的皮肤肥大细胞增多症，乳晕部分受累。先前被诊断为乳头湿疹，患者对 III 类和 IV 类外用皮质类固醇的治疗反应不佳。鉴于它是成人发病，治疗反应不佳，且临床表现不典型，因此进行了活检，结果显示皮肤肥大细胞增多症。皮肤科医生在鉴别诊断乳头性皮炎时可能会考虑这另一种临床诊断。
