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鼻腔鼻窦畸胎癌肉瘤:病例报告及文献复习。

Sinonasal teratocarcinosarcoma: a case report and literature review.

机构信息

Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.

出版信息

J Int Med Res. 2020 Dec;48(12):300060520971488. doi: 10.1177/0300060520971488.

Abstract

BACKGROUND

Sinonasal teratocarcinosarcoma (SNTCS) is a highly invasive malignant tumor most frequently found in the nasal cavity and paranasal sinuses. As a result, it can be confused with other sinonasal tumors. In addition, SNTCS progresses rapidly and often infiltrates other tissues or organs in the early phase, resulting in poor patient prognosis. The objective of this article was to report the case of a patient with SNTCS and discuss the management strategy. Furthermore, we conducted a literature review for SNTCS and summarized the findings from 107 cases. Here, we report a 47-year-old man diagnosed with SNTCS and treated with radiochemotherapy after an initial operation. After follow-up for 5 years, no tumor recurrence was observed.

CONCLUSIONS

As SNTCS progresses rapidly, early diagnosis and surgical treatment combined with radiochemotherapy can improve patient survival.

摘要

背景

鼻窦胚细胞瘤肉瘤(SNTCS)是一种高度侵袭性的恶性肿瘤,最常发生在鼻腔和鼻窦。因此,它可能与其他鼻窦肿瘤混淆。此外,SNTCS 进展迅速,早期常浸润其他组织或器官,导致患者预后不良。本文旨在报告一例 SNTCS 患者,并讨论其治疗策略。此外,我们对 SNTCS 进行了文献复习,并总结了 107 例病例的结果。在这里,我们报告了一例 47 岁男性患者,诊断为 SNTCS,在初次手术后接受放化疗。随访 5 年后,未观察到肿瘤复发。

结论

由于 SNTCS 进展迅速,早期诊断和手术治疗联合放化疗可以提高患者的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be2b/7754799/2fb2a1cf009b/10.1177_0300060520971488-fig1.jpg

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