Savoia D, Vulcano F, Martinotti M G
Istituto di Microbiologia, Università di Torino.
G Batteriol Virol Immunol. 1987 Jan-Dec;80(1-12):3-13.
We examined the surface characteristics of four group A Streptococcus strains in log or stationary phase of growth by using the techniques of salt aggregation and of adhesion to n-hexadecane. By means of the former technique a greater correlation was observed between surface hydrophobicity and production of M protein (above all in stationary phase of bacteria). Using the latter one, we noted differences depending on the growth phase, but not related to M protein. The pretreatment of bacteria with subCMI of clindamycin decreases their hydrophobicity, particularly in M+ strains and in stationary phase of growth. Less variations of surface were observed in M- strains and after treatment with subCMI of imipenem.
我们通过盐聚集和对正十六烷的黏附技术，研究了处于对数生长期或稳定生长期的四株A组链球菌菌株的表面特性。通过前一种技术，观察到表面疏水性与M蛋白产生之间存在更大的相关性（尤其是在细菌的稳定期）。使用后一种技术时，我们注意到存在取决于生长阶段的差异，但与M蛋白无关。用克林霉素亚抑菌浓度对细菌进行预处理会降低其疏水性，特别是在M+菌株和生长稳定期。在M-菌株中以及用亚胺培南亚抑菌浓度处理后，观察到的表面变化较少。
