Jimbo-Sotomayor Ruth, Armijos-Acurio Luciana, Proaño-Espinosa José, Segarra-Galarza Katy, Sánchez-Choez Xavier
Pontifical Catholic University of Ecuador, Graduate School of Family and Community Medicine, Quito, Ecuador.
Alcalá De Henares University, Alcalá De Henares, España.
J Glob Infect Dis. 2020 Aug 29;12(3):124-128. doi: 10.4103/jgid.jgid_125_19. eCollection 2020 Jul-Sep.
Studies have shown that pneumococcal disease significantly increases morbidity and mortality rates in children 5 years old and under. These infections constitute the main cause of preventable deaths in the world, considering the availability of vaccination. Considering that Ecuador is in a high incidence region, despite the introduction of the vaccine, this study aims to describe the burden of hospitalized pneumococcal disease and related mortality in our country between 2005 and 2015, to help decision-making processes for the health authorities.
This cross-sectional study analyzes morbidity, mortality, and the situation in Ecuador caused by pneumococcal disease in children 5 years old and under between 2005 and 2015 using national databases.
A total of 163,852 cases of children 5 years old and under were reported to have been hospitalized due to pneumococcal-related diseases. Males comprised 54.7% of the cases and females 45.3%. In 36% of the cases, the patients were 1 year old or under. The mortality rate due to pneumococcal disease in Ecuador in children aged 5 and under decreased in 48% during 2005-2015.
The decrease in mortality can be related to the introduction of the vaccine and an increase in access to health care by the general population in the country. It is important to study the specific impact of the vaccine in the reduction of morbidity and mortality of children in Ecuador.
研究表明,肺炎球菌疾病显著增加了5岁及以下儿童的发病率和死亡率。考虑到疫苗的可及性,这些感染是全球可预防死亡的主要原因。鉴于厄瓜多尔属于高发病率地区,尽管已引入疫苗,但本研究旨在描述2005年至2015年间我国住院肺炎球菌疾病的负担及相关死亡率,以协助卫生当局进行决策。
这项横断面研究利用国家数据库分析了2005年至2015年间5岁及以下儿童因肺炎球菌疾病在厄瓜多尔引发的发病率、死亡率及相关情况。
总共报告了163,852例5岁及以下儿童因肺炎球菌相关疾病住院。其中男性占病例的54.7%,女性占45.3%。36%的病例中患者年龄为1岁及以下。2005 - 2015年间,厄瓜多尔5岁及以下儿童因肺炎球菌疾病导致的死亡率下降了48%。
死亡率的下降可能与疫苗的引入以及该国普通民众获得医疗保健的机会增加有关。研究疫苗对降低厄瓜多尔儿童发病率和死亡率的具体影响非常重要。