Nobue Ayaka, Kunimasa Yoko, Tsuneishi Hiromu, Sano Kanae, Oda Hiroyuki, Ishikawa Masaki
Faculty of Health Sciences, Morinomiya University of Medical Sciences, Osaka, Japan.
Graduate School of Sport and Exercise Sciences, Osaka University of Health and Sport Sciences, Osaka, Japan.
Front Physiol. 2020 Dec 3;11:609006. doi: 10.3389/fphys.2020.609006. eCollection 2020.
This study aimed to simultaneously examine the differences of human nerve conduction velocity (NCV) and nerve cross-sectional area (nCSA) between the upper and lower limbs and between different regions of the upper and lower limbs. Thirty healthy subjects volunteered for the study. NCV and nCSA of the ulnar and tibial nerves were measured with the dominant and non-dominant arms and the supporting and reacting legs using supramaximal electric stimulation and peripheral nerve ultrasonography at three regions for ulnar and tibial nerves, respectively. Supramaximal electric stimulation was superficially applied to the ulnar and tibial nerves at each point. These action potentials were recorded from the digiti minimi and soleus muscles for the ulnar and tibial nerves, respectively. Our results clearly showed that the NCV, nCSA, and circumference of the ulnar and tibial nerves were higher and greater in the lower limbs than in the upper limbs. The greater the circumference, the greater the nCSA for both the upper and lower limbs. However, unlike the upper limbs, the supporting leg did not have higher NCV than the reacting leg despite its greater circumference. Therefore, nCSA can be related to the circumference but not necessarily function for NCV developments of the lower limbs. These various aspects between the upper and lower limbs suggest that NCV does not depend on the nCSA sizes or upper and lower limb circumference; the results indicate the existence of limb-specific NCV but not nCSA developments.
本研究旨在同时检测人体上肢与下肢之间以及上下肢不同区域之间神经传导速度（NCV）和神经横截面积（nCSA）的差异。30名健康受试者自愿参与本研究。分别在尺神经和胫神经的三个区域，使用超强电刺激和周围神经超声检查，测量优势臂与非优势臂以及支撑腿与反应腿的尺神经和胫神经的NCV和nCSA。在每个点对尺神经和胫神经表面施加超强电刺激。分别从尺神经和胫神经的小指展肌和比目鱼肌记录这些动作电位。我们的结果清楚地表明，尺神经和胫神经的NCV、nCSA以及周长在下肢均高于上肢且大于上肢。对于上肢和下肢，周长越大，nCSA越大。然而，与上肢不同，支撑腿尽管周长更大，但NCV并不高于反应腿。因此，nCSA可能与周长有关，但对于下肢NCV的发育不一定起作用。上肢和下肢之间的这些不同方面表明，NCV并不取决于nCSA大小或上下肢周长；结果表明存在肢体特异性的NCV，但不存在nCSA发育的差异。
