Song Xiao-Le, Yang Jing-Yi, Lai Yu-Ting, Zhou Jia-Ying, Wang Jing-Jing, Sun Xi-Cai, Wang De-Hui
Department of Otorhinolaryngology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
World J Clin Cases. 2020 Nov 26;8(22):5684-5689. doi: 10.12998/wjcc.v8.i22.5684.
Here we present a rare case of localized amyloidosis involving the nasolacrimal duct and lacrimal sac which was managed by endoscopic surgery.
A 50-year-old man whose medical history included bilateral ventricular fold and vocal cord amyloidosis complained of bilateral epiphora. Magnetic resonance imaging revealed a neoplasm within the nasolacrimal sac. Characteristic positivity for Congo red staining and birefringence under a polarized microscope proved the diagnosis of amyloidosis. Dacryocystorhinostomy an endoscope obtained a favorable result. A one-year follow-up found no recurrence.
There are few reports on amyloidosis involving the lacrimal outflow system, and management and outcome are not clear. Endoscopic dacryocystorhinostomy can be a choice to relieve symptoms. Regular follow-up and monitoring of systemic diseases are highly recommended.
在此我们呈现一例罕见的局限性淀粉样变性病例,病变累及鼻泪管和泪囊,通过内镜手术进行治疗。
一名50岁男性,既往病史包括双侧室襞和声带淀粉样变性,主诉双侧溢泪。磁共振成像显示泪囊内有一肿物。刚果红染色阳性及在偏振显微镜下出现双折射现象,证实为淀粉样变性。采用内镜下泪囊鼻腔吻合术取得了良好效果。一年的随访未发现复发。
关于累及泪液引流系统的淀粉样变性报道较少,其治疗方法和预后尚不清楚。内镜下泪囊鼻腔吻合术可作为缓解症状的一种选择。强烈建议定期随访并监测全身性疾病。