胃混合性腺瘤-神经内分泌肿瘤：一例报告。
Gastric mixed adenoma-neuroendocrine tumor: A case report.
作者信息
Kohno Shuzo, Aoki Hiroaki, Kato Masayuki, Ogawa Masaich, Yoshida Kazuhiko
机构信息
Department of Surgery, The Jikei University Katsushika Medical Center, Tokyo 125-8506, Katsushika-ku, Japan.
Department of Endoscopy, The Jikei University Katsushika Medical Center, Tokyo 125-8506, Katsushika-ku, Japan.
出版信息
World J Clin Cases. 2020 Nov 26;8(22):5744-5750. doi: 10.12998/wjcc.v8.i22.5744.
BACKGROUND
Gastric mixed adenoma-neuroendocrine tumors (NETs) are quite rare. In the 2019 world health organization classification of tumors of the digestive system, these were designated as a combination of grade 1 or grade 2 NETs and adenomas or tubular adenomas. There are no treatment guidelines for these tumors, and pathological and clinical studies are ongoing. Herein, we review previous case reports and present a case of gastric mixed adenoma-NET.
CASE SUMMARY
A 66-year-old man underwent gastrointestinal endoscopy for the evaluation of upper abdominal pain. Histopathological examination of the biopsy specimen indicated the possibility of gastric cancer. A histopathological examination by endoscopic submucosal dissection showed a mixed adenoma-NET that was completely excised by endoscopic submucosal dissection. No recurrence was observed on gastrointestinal endoscopy at the 6-mo follow-up.
CONCLUSION
Clinicians' awareness of this rare tumor is important for its timely diagnosis and treatment.
背景
胃混合性腺瘤-神经内分泌肿瘤（NETs）非常罕见。在2019年世界卫生组织消化系统肿瘤分类中，这些肿瘤被指定为1级或2级NETs与腺瘤或管状腺瘤的组合。目前尚无针对这些肿瘤的治疗指南，相关病理和临床研究正在进行中。在此，我们回顾既往病例报告并呈现1例胃混合性腺瘤-NET病例。
病例摘要
一名66岁男性因上腹部疼痛接受胃肠内镜检查。活检标本的组织病理学检查提示胃癌可能。经内镜黏膜下剥离术进行的组织病理学检查显示为混合性腺瘤-NET，通过内镜黏膜下剥离术将其完全切除。6个月随访时胃肠内镜检查未观察到复发。
结论
临床医生对这种罕见肿瘤的认识对于其及时诊断和治疗很重要。
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