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整体理论指导下的腹腔镜全盆底/韧带修复术治疗女性直肠内脱垂的临床疗效

Clinical efficacy of integral theory-guided laparoscopic integral pelvic floor/ligament repair in the treatment of internal rectal prolapse in females.

作者信息

Yang Yang, Cao Yong-Li, Zhang Yuan-Yao, Shi Shou-Sen, Yang Wei-Wei, Zhao Nan, Lyu Bing-Bing, Zhang Wen-Li, Wei Dong

机构信息

Institute of Anal-Colorectal Surgery, the 989 Hospital of The Joint Logistics Support Force of PLA, Luoyang 471031, Henan Province, China.

出版信息

World J Clin Cases. 2020 Dec 6;8(23):5876-5886. doi: 10.12998/wjcc.v8.i23.5876.

Abstract

BACKGROUND

Internal rectal prolapse (IRP) is one of the most common causes of obstructive constipation. The incidence of IRP in women is approximately three times that in men. IRP is mainly treated by surgery, which can be divided into two categories: Abdominal procedures and perineal procedures. This study offers a better procedure for the treatment of IRP.

AIM

To compare the clinical efficacy of laparoscopic integral pelvic floor/ligament repair (IPFLR) combined with a procedure for prolapse and hemorrhoids (PPH) and the laparoscopic IPFLR alone in the treatment of IRP in women.

METHODS

This study collected the clinical data of 130 female patients with IRP who underwent surgery from January 2012 to October 2014. The patients were divided into groups A and B. Group A had 63 patients who underwent laparoscopic IPFLR alone, and group B had 67 patients who underwent the laparoscopic IPFLR combined with PPH. The degree of internal rectal prolapse (DIRP), Wexner constipation scale (WCS) score, Wexner incontinence scale (WIS) score, and Gastrointestinal Quality of Life Index (GIQLI) score were compared between groups and within groups before surgery and 6 mo and 2 years after surgery.

RESULTS

All laparoscopic surgeries were successful. The general information, number of bowel movements before surgery, DIRP, GIQLI score, WIS score, and WCS score before surgery were not significantly different between the two groups (all > 0.05). The WCS score, WIS score, GIQLI score, and DIRP in each group 6 mo, and 2 years after surgery were significantly better than before surgery ( 0.001). In group A, the DIRP and WCS score gradually improved from 6 mo to 2 years after surgery ( < 0.001), and the GIQLI score progressively improved from 6 mo to 2 years after surgery ( < 0.05). In group B, the DIRP, WCS score and WIS score significantly improved from 6 mo to 2 years after surgery ( < 0.05), and the GIQLI score 2 years after surgery was significantly higher than that 6 mo after surgery ( < 0.05). The WCS score, WIS score, GIQLI score, and DIRP of group B were significantly better than those of group A 6 mo and 2 years after surgery (all < 0.001, Bonferroni) except DIRP at 2 years after surgery. There was a significant difference in the recurrence rate of IRP between the two groups 6 mo after surgery ( = 0.011). There was no significant difference in postoperative grade I-III complications between the two groups ( = 0.822).

CONCLUSION

Integral theory-guided laparoscopic IPFLR combined with PPH has a higher cure rate and a better clinical efficacy than laparoscopic IPFLR alone.

摘要

背景

直肠内脱垂(IRP)是梗阻性便秘最常见的病因之一。女性IRP的发病率约为男性的三倍。IRP主要通过手术治疗,手术可分为两类:腹部手术和会阴手术。本研究提供了一种更好的IRP治疗方法。

目的

比较腹腔镜全盆底/韧带修复术(IPFLR)联合吻合器痔上黏膜环切术(PPH)与单纯腹腔镜IPFLR治疗女性IRP的临床疗效。

方法

本研究收集了2012年1月至2014年10月接受手术治疗的130例女性IRP患者的临床资料。将患者分为A组和B组。A组63例患者仅接受腹腔镜IPFLR,B组67例患者接受腹腔镜IPFLR联合PPH。比较两组患者手术前、术后6个月和2年时的直肠内脱垂程度(DIRP)、韦克斯纳便秘量表(WCS)评分、韦克斯纳失禁量表(WIS)评分和胃肠道生活质量指数(GIQLI)评分,以及组内不同时间点的上述指标。

结果

所有腹腔镜手术均成功。两组患者的一般资料、术前排便次数、DIRP、GIQLI评分、WIS评分和WCS评分术前比较差异均无统计学意义(均>0.05)。两组患者术后6个月和2年时的WCS评分、WIS评分、GIQLI评分和DIRP均明显优于术前(均<0.001)。A组患者术后6个月至2年DIRP和WCS评分逐渐改善(均<0.001),GIQLI评分术后6个月至2年逐渐升高(<0.05)。B组患者术后6个月至2年DIRP、WCS评分和WIS评分明显改善(均<0.05),术后2年GIQLI评分明显高于术后6个月(<0.05)。术后6个月和2年时,B组患者的WCS评分、WIS评分、GIQLI评分和DIRP均明显优于A组(均<0.001,Bonferroni法),术后2年DIRP除外。两组患者术后6个月IRP复发率比较差异有统计学意义(P = 0.011)。两组患者术后Ⅰ-Ⅲ级并发症发生率比较差异无统计学意义(P = 0.822)。

结论

整体理论指导下的腹腔镜IPFLR联合PPH治疗女性IRP较单纯腹腔镜IPFLR治愈率更高,临床疗效更好。

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