Cancer Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Int J STD AIDS. 2021 Mar;32(4):352-360. doi: 10.1177/0956462420967576. Epub 2020 Dec 20.
The age of patients living with human immunodeficiency virus (HIV) is increasing and the greatest proportion of aged HIV patients occurred in Western and Central Europe and North America (WCENA). In aged HIV patients in WCENA, older MSM is the main population. The aim of our study was to evaluate the HIV prevalence in older MSM in WCENA. A meta-analysis was conducted. We searched Medline, Embase, PsycINFO, Web of Science, Cochrane library, Ageline databases, and government websites. Studies that estimated HIV prevalence in older MSM in WCENA were selected. The pooled HIV prevalence and odds ratio (OR) of the risk of living with HIV in older MSM were calculated. In total of 23000 records were initially records were identified and 12 records were included. The total sample size of older MSM was 6118. The pooled HIV prevalence in older MSM in WCENA was 26% (95% CI 18%-33%), which was much higher than that in younger MSM (18%, 95% CI 14%-21%). Notably, the HIV prevalence in older MSM has been continuously increasing in the past two decades in WCENA, raising from 16% to 33%. The pooled OR for older MSM to be living with HIV was 1.68 compared to younger MSM. The HIV prevalence in older MSM in WCENA is disproportionately high, with a continuously increasing trend in the past two decades. Older MSM also carry significantly higher risk of living with HIV than younger MSM.
HIV 感染者的年龄正在增长，在西欧、中欧和北美（WCENA），年龄最大的 HIV 感染者比例最高。在 WCENA 的老年 HIV 感染者中，年长的男男性行为者（MSM）是主要人群。我们的研究目的是评估 WCENA 年长的男男性行为者中的 HIV 流行率。进行了一项荟萃分析。我们检索了 Medline、Embase、PsycINFO、Web of Science、Cochrane 图书馆、Ageline 数据库和政府网站。选择了估计 WCENA 年长的男男性行为者中 HIV 流行率的研究。计算了年长的男男性行为者中 HIV 流行率的合并率和感染 HIV 的风险比（OR）。最初共确定了 23000 份记录，纳入了 12 份记录。年长的男男性行为者的总样本量为 6118 人。WCENA 年长的男男性行为者中 HIV 的合并流行率为 26%（95%CI 18%-33%），远高于年轻的男男性行为者（18%，95%CI 14%-21%）。值得注意的是，在过去的二十年中，WCENA 年长的男男性行为者中 HIV 的流行率一直在持续上升，从 16%上升到 33%。与年轻的男男性行为者相比，年长的男男性行为者感染 HIV 的合并 OR 为 1.68。WCENA 年长的男男性行为者中 HIV 的流行率过高，且在过去二十年中呈持续上升趋势。年长的男男性行为者感染 HIV 的风险也明显高于年轻的男男性行为者。
