Sri Sathya Sai Institute of Higher Medical Sciences, Department of Urology, Prashantigram, Puttaparthi, Andhra Pradesh 515134, India.
J Bras Nefrol. 2022 Apr-Jun;44(2):281-284. doi: 10.1590/2175-8239-JBN-2019-0127.
Ascites and oliguria with an increasing serum creatinine level are often observed in patients with acute renal failure. However, these symptoms are also noted in individuals with intraperitoneal urinary leakage and can be mistaken for acute renal failure. This rise in creatinine in such patients is called pseudo renal failure and it happens by a process of reverse peritoneal dialysis. In literature, the most commonly described condition that leads to this clinical picture is following a spontaneous or missed bladder perforation. We, herein, report a case of carcinoma of the bladder that presented with features resembling acute renal failure, which later turned out to be pseudo renal failure due to intraperitoneal urinary extravasation from a forniceal rupture. The patient was managed with emergency with a percutaneous drain followed by a percutaneous nephrostomy, which led to normalization of creatinine. Cystoscopy revealed the bladder growth in an intact small capacity bladder and biopsy confirmed it as a muscle invasive squamous cell carcinoma. Due to advanced nature of his malignancy, he underwent a palliative ileal conduit diversion but he later developed chest metastasis and ultimately succumbed to the disease. Intraperitoneal urinary leakage due to forniceal rupture presenting as pseudo renal failure is a rare presentation of carcinoma bladder. Sudden onset abdominal discomfort, increasing ascites, hematuria, and oliguria with elevated renal parameters needs consideration and exclusion of this entity. The diagnostic dilemma associated with this rare presentation along with the management and prognosis in such patients of carcinoma bladder are discussed.
腹水和少尿伴有血清肌酐水平升高,常发生在急性肾衰竭患者中。然而,这些症状也见于腹腔内尿漏患者,可误诊为急性肾衰竭。此类患者肌酐升高称为假性肾衰竭,其发生是通过腹膜透析反向过程。在文献中,最常描述的导致这种临床表现的情况是自发性或漏诊的膀胱穿孔。在此,我们报告一例膀胱癌患者,其表现类似于急性肾衰竭,后来由于穹窿破裂导致腹腔内尿外渗而发生假性肾衰竭。患者接受了紧急经皮引流和经皮肾造口术,随后肌酐恢复正常。膀胱镜检查显示膀胱内有完整的小容量膀胱生长,活检证实为肌层浸润性鳞状细胞癌。由于恶性肿瘤的晚期性质,他接受了姑息性回肠造口术,但后来出现了胸部转移,最终死于该疾病。穹窿破裂引起的腹腔内尿漏导致假性肾衰竭是膀胱癌的罕见表现。突发的腹部不适、腹水增加、血尿和少尿伴有肾功能参数升高,需要考虑并排除这种情况。讨论了这种罕见表现相关的诊断困境以及此类膀胱癌患者的治疗和预后。