Wang Tao, Liu Ji-Hong
Department of Urology, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Research Institute of Urology, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Zhonghua Nan Ke Xue. 2020 Mar;26(3):195-199.
In December 2019, the novel coronavirus pneumonia broke out in Wuhan, Hubei, and then spread across China and the world, which posed a threat to public health and safety.The symptoms caused by the novel coronavirus (SARS-CoV-2) mainly involve the respiratory system, but no literature has been reported whether it can induce pathological changes in the male reproductive system. According to the fact that SARS-CoV-2 can infect the cells expressing angiotensin-converting enzyme 2 (ACE2), which can be distributed in the corpus cavernosum, testis and other male reproductive organs and may also participate in erectile function, spermatogenesis, sperm motility and androgen metabolism through the ACE2-Ang-(1-7)-Mas axis in the renin-angiotensin system(RAS), it can be deduced that SARS-CoV-2 may affect these physiological processes of male reproduction.