Veronese Nicola, Kolk Helgi, Maggi Stefania
National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
Hip fracture is an important and debilitating condition in older people, especially in women. The epidemiological data vary between countries, but it is globally estimated that hip fractures currently affect around 18% of women and 6% of men. Although the age-standardised incidence is gradually decreasing in many countries, this is far outweighed by the ageing of the population. Thus, the global number of hip fractures is expected to increase. The direct costs associated with this condition are enormous since it requires a long period of hospitalisation and subsequent rehabilitation. Furthermore, hip fracture is associated with the development of other negative consequences, such as disability, depression, and cardiovascular diseases, with additional costs for society. At the same time, increasing attention is given to other osteoporotic fractures, such as vertebral ones, that are associated with negative health outcomes and enormous costs. In this chapter, we describe the most recent epidemiological data regarding hip and other osteoporotic fractures, with special attention to the well-known risk factors and conditions that seem relevant for determining fractures in older people. A specific part is dedicated to the social costs due to fractures. Although the costs of hip fracture are probably comparable to other common diseases with a high hospitalisation rate (e.g. cardiovascular disease), the other social costs (due to onset of new comorbidities, sarcopenia, poor quality of life, disability and mortality) are probably greater.
髋部骨折是老年人尤其是女性中一种重要且使人衰弱的疾病。各国的流行病学数据有所不同,但据全球估计,目前髋部骨折影响约18%的女性和6%的男性。尽管在许多国家年龄标准化发病率在逐渐下降,但这远远被人口老龄化所抵消。因此,全球髋部骨折的数量预计将会增加。与这种疾病相关的直接成本巨大,因为它需要长时间住院及随后的康复治疗。此外,髋部骨折还与其他负面后果的发生相关,如残疾、抑郁和心血管疾病,给社会带来额外成本。与此同时,人们越来越关注其他骨质疏松性骨折,如椎体骨折,它们与负面健康结果及巨大成本相关。在本章中,我们描述了关于髋部和其他骨质疏松性骨折的最新流行病学数据,特别关注那些与确定老年人骨折似乎相关的已知风险因素和状况。有一个特定部分专门讨论骨折造成的社会成本。尽管髋部骨折的成本可能与其他住院率高的常见疾病(如心血管疾病)相当,但其他社会成本(由于新合并症的出现、肌肉减少症、生活质量差、残疾和死亡率)可能更高。