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钝挫伤对视网膜微血管的影响:光学相干断层扫描血管造影研究。

Effect of blunt ocular trauma on retinal microvasculature: An optical coherence tomography angiography study.

机构信息

Cumhuriyet University, Faculty of Medicine, Department of Ophthalmology, 58140, Sivas, Turkey.

University of Health Sciences, Gulhane Training and Research Hospital, Department of Ophthalmology, 06010 Ankara, Turkey.

出版信息

Photodiagnosis Photodyn Ther. 2021 Mar;33:102147. doi: 10.1016/j.pdpdt.2020.102147. Epub 2021 Jan 4.

DOI:10.1016/j.pdpdt.2020.102147
PMID:33348078
Abstract

BACKGROUND

To evaluate the retinal vascular changes and foveal avascular zone area in patients with unilateral blunt ocular trauma using optical coherence tomography angiography.

METHODS

This retrospective study consisted of 50 traumatized and 50 contralateral sound eyes of the patients with blunt ocular trauma. The foveal avascular zone area, choriocapillaris flow area, foveal, parafoveal, and perifoveal vessel densities in both superficial capillary plexus and deep capillary plexus and central macular thickness were evaluated.

RESULTS

There were no significant differences between traumatized and sound eyes in the foveal avascular zone area (p:0.36), choriocapillaris flow area (p:0.43), central macular thickness (p:0.67), and in vessel densities of superficial capillary plexus over all regions (p > 0.05 for all). However, the vessel densities of deep capillary plexus were significantly lower in traumatized eyes (p < 0.05 for all).

CONCLUSION

Optical coherence tomography angiography demonstrated a significant decrease in retinal deep capillary plexus vessel density of the eyes effected by blunt ocular trauma, even with no evident findings on fundus examination or structural spectral domain-optical coherence tomography changes.

摘要

背景

应用光学相干断层扫描血管造影术评估单侧钝挫伤患者的视网膜血管变化和黄斑中心无血管区面积。

方法

本回顾性研究纳入 50 例单侧钝挫伤患者的受累眼和对侧正常眼。评估黄斑中心无血管区面积、脉络膜毛细血管血流面积、浅层毛细血管丛和深层毛细血管丛的中心凹、旁中心凹和中心凹周围视网膜血管密度以及黄斑中心厚度。

结果

受累眼与正常眼的黄斑中心无血管区面积(p:0.36)、脉络膜毛细血管血流面积(p:0.43)、黄斑中心厚度(p:0.67)以及浅层毛细血管丛各区域的血管密度差异均无统计学意义(p > 0.05)。然而,深层毛细血管丛的血管密度在受累眼中显著降低(p < 0.05)。

结论

即使在眼底检查或结构谱域光学相干断层扫描无明显发现的情况下,光学相干断层扫描血管造影术也显示出钝挫伤眼视网膜深层毛细血管丛血管密度显著降低。

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