Department of Oral Diagnosis, School of Dentistry, 28119Federal University of Uberlandia. Minas Gerais, Brazil.
Division of Comprehensive Oral Health, School of Dentistry, 2331University of North Carolina. Chapel Hill, NC, USA.
Cleft Palate Craniofac J. 2021 Sep;58(9):1102-1109. doi: 10.1177/1055665620980226. Epub 2020 Dec 21.
To evaluate the occurrence of cervical vertebrae anomalies (CVA) in patients with unilateral (UCLP) and bilateral cleft lip and palate (BCLP) using cone beam computed tomography (CBCT) examinations.
Retrospective assessment of CBCT images. Descriptive statistics were calculated. Fisher exact test or χ test was performed to evaluate the differences among each CVA between sex and type of cleft.
School of Dentistry.
One hundred fifty-one patients with cleft lip and palate (103 UCLP/48 BCLP).
No relevant intervention.
Cone beam computed tomography images were assessed for the presence or absence of 12 most commonly observed CVA: spina bifida, dehiscence, cleft of the posterior arch, cleft of the anterior arch, fusion between cervical vertebrae, block fusion, occipitalization, narrowing of the intervertebral space, posterior ponticle, , , and subdental cartilaginous remnants.
The presence of subdental cartilaginous remnants was the most frequently observed alteration-found in 81.45% of the sample-and it was the only CVA with statistically significant frequencies in the individuals with BCLP. Considering only the other CVA, 22.51% presented 1 and 5.29% presented 2 or more CVA.
Patients with cleft lip and palate may present an overall high incidence of CVAs. However, when comparing the distribution of the CVAs among sex and types of cleft, the only significant difference noted was a higher incidence of subdental cartilaginous remnants among patients with BCLP.
使用锥形束 CT（CBCT）评估单侧唇腭裂（UCLP）和双侧唇腭裂（BCLP）患者颈椎异常（CVA）的发生情况。
CBCT 图像的回顾性评估。计算描述性统计数据。使用 Fisher 确切检验或 χ 检验评估性别和裂隙类型之间每种 CVA 的差异。
牙科学院。
151 例唇腭裂患者（103 例 UCLP/48 例 BCLP）。
无相关干预措施。
评估存在或不存在 12 种最常见观察到的 CVA 的 CBCT 图像：脊柱裂、裂隙、后弓裂隙、前弓裂隙、颈椎融合、块状融合、枕骨化、椎间隙变窄、后 ponticle、、、和齿下软骨残余物。
齿下软骨残余物的存在是最常见的观察到的改变-在样本中发现了 81.45%-并且是 BCLP 患者中具有统计学意义的频率的唯一 CVA。仅考虑其他 CVA，22.51%的患者出现 1 种，5.29%的患者出现 2 种或更多 CVA。
唇腭裂患者可能存在总体较高的 CVA 发生率。然而，当比较性别和裂隙类型之间 CVA 的分布时，唯一注意到的显著差异是 BCLP 患者中齿下软骨残余物的发生率较高。
