Brar Sabrina, Watters Carolina, Winters Ryan
St George's University Hospital
Bristol Medical School
Chronic suppurative otitis media (CSOM), characterized by repeated or prolonged episodes of acute otitis media lasting for more than 12 weeks, can cause damage to the tympanic membrane (TM) and result in a non-healing perforation. Worldwide, CSOM is the most common childhood infectious disease. Risk factors include upper respiratory tract infection, malnutrition, poor hygiene, family history, low birth weight, craniofacial anomalies, and being of Native American, Native Alaskan, or Aboriginal Australian ancestry. The symptoms of CSOM are otorrhoea that leaks into the external ear canal through the TM perforation and hearing loss. The hearing loss is typically a mild conductive loss (10 to 20dB), though this may be worse with large perforations. Additionally, ossicular chain erosion can occur in some cases, causing a more profound audiologic alteration (50 to 70dB). It is crucial to exclude the presence of cholesteatoma in such instances. Tympanic membrane perforations may present in either the pars tensa or pars flaccida (though the former is by far the most common). The perforation can be further described as marginal or central depending on the position relative to the annulus, as well as wet or dry (persistent otorrhoea or no active otorrhoea, respectively). A subtype of CSOM is CSOM with cholesteatoma. Cholesteatomas are most commonly an acquired disease process occurring within the middle ear. They consist of a sac of squamous epithelium, usually in the attic and originating at the pars falccida of the TM, which can extend beyond the TM, eroding bone and thereby causing ossicular chain destruction. Signs and symptoms of cholesteatoma are similar to CSOM and include foul-smelling otorrhoea, hearing loss, TM perforation, and attic retraction. Please see the StatPearls article entitled "cholesteatoma." Tympanoplasty is the surgical procedure performed to repair a perforated TM, with or without reconstruction of the ossicles (ossiculoplasty), aiming to prevent reinfection and restore hearing ability. CSOM is the most common indication; large invasive cholesteatomas may require a mastoidectomy as well as reconstruction of the TM. The history of tympanoplasty began in the 1950s when Wullstein and Zollner popularized the technique of using overlay graft to reconstruct the perforated TM and restore the sound conduction apparatus of the middle ear. Since then, surgical approaches to tympanoplasty have been modified, as described herein. Tympanoplasty can be classified into five types, according to the Wullstein classification. Type I: repair of the TM alone; no middle ear abnormality. Type I tympanoplasty is synonymous with myringoplasty. Type II: repair of the TM and middle ear; the malleus is eroded. Tympanoplasty involves grafting the TM to the incus. Type III: repair of the TM onto the stapes head; the malleus and incus have a defect. Type IV: the TM is grafted to the stapes footplate, which is movable. Type V: repair involves the stapes footplate, which is fixed.
慢性化脓性中耳炎(CSOM)的特征是急性中耳炎反复发作或持续时间延长超过12周,可导致鼓膜(TM)受损并造成不愈合的穿孔。在全球范围内,CSOM是最常见的儿童期传染病。危险因素包括上呼吸道感染、营养不良、卫生条件差、家族史、低出生体重、颅面畸形以及具有美洲原住民、阿拉斯加原住民或澳大利亚原住民血统。CSOM的症状是通过TM穿孔漏入外耳道的耳漏和听力损失。听力损失通常为轻度传导性损失(10至20分贝),不过大穿孔时可能更严重。此外,在某些情况下可发生听骨链侵蚀,导致更严重的听力改变(50至70分贝)。在此类情况下排除胆脂瘤的存在至关重要。鼓膜穿孔可出现在紧张部或松弛部(尽管前者最为常见)。根据相对于鼓环的位置,穿孔可进一步描述为边缘性或中央性,以及湿性或干性(分别为持续性耳漏或无活动性耳漏)。CSOM的一种亚型是伴有胆脂瘤的CSOM。胆脂瘤最常见于中耳内发生的后天性疾病过程。它们由一层鳞状上皮囊组成,通常位于上鼓室且起源于TM的松弛部,可延伸至TM之外,侵蚀骨质,从而导致听骨链破坏。胆脂瘤的体征和症状与CSOM相似,包括恶臭的耳漏、听力损失、TM穿孔和上鼓室回缩。请参阅标题为 “胆脂瘤” 的StatPearls文章。鼓室成形术是用于修复穿孔TM的外科手术,可伴有或不伴有听骨重建(听骨成形术),旨在防止再次感染并恢复听力。CSOM是最常见的适应证;大型侵袭性胆脂瘤可能需要进行乳突切除术以及TM重建。鼓室成形术的历史始于20世纪50年代,Wullstein和Zollner推广了使用覆盖移植物重建穿孔TM并恢复中耳传音装置的技术。从那时起,鼓室成形术的手术方法已经得到改进,如下所述。根据Wullstein分类,鼓室成形术可分为五种类型。I型:仅修复TM;中耳无异常情况。I型鼓室成形术与鼓膜成形术同义。II型:修复TM和中耳;锤骨被侵蚀。鼓室成形术包括将TM移植到砧骨上。III型:将TM修复到镫骨头;锤骨和砧骨有缺损。IV型:将TM移植到可活动的镫骨足板上。V型:修复涉及固定的镫骨足板。