Resident, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China; and, Department of Oral Radiology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Associate Professor, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China; and, Department of Oral Radiology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
J Oral Maxillofac Surg. 2021 Jun;79(6):1255-1261. doi: 10.1016/j.joms.2020.11.021. Epub 2020 Nov 26.
The aim of the study was to compare the clinical and cone-beam computed tomography features of orthokeratinized odontogenic cysts (OOCs) and odontogenic keratocysts (OKCs) and to fully understand features of these 2 odontogenic cysts.
This retrospective cross-sectional study included patients with mandibular OOCs and OKCs. The predictor variables included age at the time of diagnosis, sex, anatomical location of the cysts, lesion size, cortical bone expansion rate, and presence of cortical bone destruction, impacted tooth, tooth displacement, and root resorption. The outcome variable was the type of cystic lesion. A 1-way analysis of variance test was used to analyze the differences among the cases of OOCs and OKCs. The specificity and sensitivity of the radiological features were calculated to differentiate OOCs from OKCs.
The sample was composed of 12 patients with OOCs and 36 patients with OKCs. The mean ages of the patients with OOCs (30.50 ± 6.14 years) and OKCs (38.39 ± 19.44 years) were concentrated in the third decade. The cystic lesions occurring in areas II and III accounted for 66.67 and 52.78% of the OOC and OKC cases, respectively. The cortical bone expansion rate of the OOC was larger than that of the unilocular OKC (OOC, 2.20 ± 1.05; OKC, 1.48 ± 0.50; P < .05). The specificity and sensitivity of unilocular or multiocular cysts to differentiate OOC from OKC were 100%, 42%, 95% confidence interval of 0.1479 to 0.3892 (P < .05) and tooth displacement were 100%, 3%, 95% confidence interval of 0.1479 to 0.3892 (P < .05).
The results of this study suggest clinical and radiological features of OOCs and OKCs mostly overlap, but OOC has distinctive characteristics. Most cystic lesions of OOC are unilocular cysts, rarely accompanied by tooth displacement. The cortical bone expansion rate is larger than that of unilocular cysts of OKC.
本研究旨在比较正角化牙源性囊肿(OOC)和牙源性角化囊性瘤(OKC)的临床和锥形束 CT 特征,以充分了解这两种牙源性囊肿的特征。
本回顾性横断面研究纳入了下颌骨 OOC 和 OKC 患者。预测变量包括诊断时的年龄、性别、囊肿的解剖位置、病变大小、皮质骨膨胀率、皮质骨破坏的存在、埋伏牙、牙齿移位和牙根吸收。结局变量为囊性病变的类型。采用单因素方差分析比较 OOC 和 OKC 病例之间的差异。计算影像学特征的特异性和敏感性,以区分 OOC 和 OKC。
样本由 12 例 OOC 患者和 36 例 OKC 患者组成。OOC 患者(30.50±6.14 岁)和 OKC 患者(38.39±19.44 岁)的平均年龄集中在第三十年。发生在 II 区和 III 区的囊性病变分别占 OOC 和 OKC 病例的 66.67%和 52.78%。OOC 的皮质骨膨胀率大于单房性 OKC(OOC,2.20±1.05;OKC,1.48±0.50;P<0.05)。单房或多房囊肿的特异性和敏感性分别为 100%、42%、95%置信区间为 0.1479 至 0.3892(P<0.05)和牙齿移位为 100%、3%、95%置信区间为 0.1479 至 0.3892(P<0.05)。
本研究结果表明,OOC 和 OKC 的临床和影像学特征大多重叠,但 OOC 具有独特的特征。OOC 的大多数囊性病变为单房性囊肿,很少伴有牙齿移位。皮质骨膨胀率大于 OKC 的单房性囊肿。