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阑尾炎护理的质量结果:识别改善护理的机会。

Quality Outcomes in Appendicitis Care: Identifying Opportunities to Improve Care.

作者信息

Kabir Syed Mohammad Umar, Bucholc Magda, Walker Carol-Ann, Sogaolu Opeyemi O, Zeeshan Saqib, Sugrue Michael

机构信息

Donegal Clinical Research Academy and Department of Surgery Letterkenny University Hospital, Letterkeny, Co. F92 AE81 Donegal, Ireland.

Intelligent Systems Research Centre, University of Ulster, Magee Campus, Londonderry BT48 7JL, UK.

出版信息

Life (Basel). 2020 Dec 18;10(12):358. doi: 10.3390/life10120358.

Abstract

INTRODUCTION

Appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention, but the variability of diagnosis and management continue to challenge the surgeons. : This study assessed patients undergoing appendectomy to identify opportunities to improve diagnostic accuracy and outcomes.

METHODS

An ethically approved retrospective cohort study was undertaken between March 2016 and March 2017 at a single university hospital of all consecutive adult and paediatric patients undergoing appendectomy. Demographic data including age, gender, co-morbidities, presentation and triage timings along with investigation, imaging and operative data were analysed. Appendicitis was defined as acute based on histology coupled with intraoperative grading with the American Association for the Surgery of Trauma (AAST) grades. Complications using the Clavien-Dindo classification along with 30-day re-admission rates and the negative appendectomy rates (NAR) were recorded and categorised greater and less than 25%. The use of scoring systems was assessed, and retrospective scoring performed to compare the Alvarado, Adult Appendicitis Score (AAS) and the Appendicitis Inflammatory Response (AIR) score. : A total of 201 patients were studied, 115 male and 86 females, of which 136/201 (67.6%) were adults and 65/201 (32.3%) paediatric. Of the adult group, 83 were male and 53 were female, and of the paediatric group, 32 were male and 33 were female. Median age was 20 years (range: 5 years to 81 years) and no patient below the age of 5 years had an appendectomy during our study period. All patients were admitted via the emergency department and median time from triage to surgical review was 2 h and 38 min, (range: 10 min to 26 h and 10 min). Median time from emergency department review to surgical review, 55 min (range: 5 min to 6 h and 43 min). Median time to operating theatre was 21 h from admission (range: 45 min to 140 h and 30 min). Out of the total patients, 173 (86.1%) underwent laparoscopic approach, 28 (13.9%) had an open approach and 12 (6.9%) of the 173 were converted to open. Acute appendicitis occurred in 166/201 (82.6%). There was no significant association between grade of appendicitis and surgeons' categorical NAR rate ( = 0.07). Imaging was performed in 118/201 (58.7%); abdominal ultrasound (US) in 53 (26.4%), abdominal computed tomography (CT) in 59 (29.2%) and both US and CT in 6 (3%). The best cut-off point was 4 (sensitivity 84.3% and specificity of 65.7%) for AIR score, 9 (sensitivity of 74.7% and specificity of 68.6%) for AAS, and 7 (sensitivity of 77.7% and specificity of 71.4%) for the Alvarado score. Twenty-four (11.9%) were re-admitted, due to pain in 16 (58.3%), collections in 3 (25%), 1 (4.2%) wound abscess, 1 (4.2%) stump appendicitis, 1 (4.2%) small bowel obstruction and 1 (4.2%) fresh rectal bleeding. CT guided drainage was performed in 2 (8.3%). One patient had release of wound collection under general anaesthetic whereas another patient had laparoscopic drain placement. A laparotomy was undertaken in 3 (12.5%) patients with division of adhesions in 1, the appendicular stump removed in 1 and 1 had multiple collections drained.

CONCLUSION

The negative appendectomy and re-admission rates were unacceptably high and need to be reduced. Minimising surgical variance with use of scoring systems and introduction of pathways may be a strategy to reduce NAR. New systems of feedback need to be introduced to improve outcomes.

摘要

引言

阑尾炎是需要手术干预的急性腹痛最常见的病因之一,但诊断和治疗的变异性持续给外科医生带来挑战。本研究评估接受阑尾切除术的患者,以确定提高诊断准确性和改善治疗结果的机会。

方法

在2016年3月至2017年3月期间,在一家大学医院对所有连续接受阑尾切除术的成年和儿科患者进行了一项经伦理批准的回顾性队列研究。分析了人口统计学数据,包括年龄、性别、合并症、症状表现和分诊时间,以及检查、影像学和手术数据。根据组织学结果并结合美国创伤外科协会(AAST)分级的术中分级,将阑尾炎定义为急性。记录使用Clavien-Dindo分类法的并发症、30天再入院率和阴性阑尾切除率(NAR),并将其分为大于和小于25%两类。评估评分系统的使用情况,并进行回顾性评分以比较阿尔瓦拉多评分、成人阑尾炎评分(AAS)和阑尾炎炎症反应(AIR)评分。共研究了201例患者,其中男性115例,女性86例,其中136/201(67.6%)为成年人,65/201(32.3%)为儿童。在成年组中,男性83例,女性53例;在儿童组中,男性32例,女性33例。中位年龄为20岁(范围:5岁至81岁),在我们的研究期间,没有5岁以下的患者接受阑尾切除术。所有患者均通过急诊科入院,从分诊到手术评估的中位时间为2小时38分钟(范围:10分钟至26小时10分钟)。从急诊科评估到手术评估的中位时间为55分钟(范围:5分钟至6小时43分钟)。从入院到手术室的中位时间为21小时(范围:45分钟至140小时30分钟)。在所有患者中,173例(86.1%)采用腹腔镜手术方式,28例(13.9%)采用开放手术方式,173例中有12例(6.9%)转为开放手术。166/201(82.6%)发生急性阑尾炎。阑尾炎分级与外科医生的分类NAR率之间无显著关联(P = 0.07)。201例中有118例(58.7%)进行了影像学检查;53例(26.4%)进行了腹部超声(US)检查,59例(29.2%)进行了腹部计算机断层扫描(CT)检查,6例(3%)同时进行了US和CT检查。AIR评分的最佳截断点为4(敏感性84.3%,特异性65.7%),AAS为9(敏感性74.7%,特异性68.6%),阿尔瓦拉多评分为7(敏感性77.7%,特异性71.4%)。24例(11.9%)患者再次入院,其中16例(58.3%)因疼痛入院,3例(25%)因积液入院,1例(4.2%)因伤口脓肿入院,1例(4.2%)因阑尾残株炎入院,1例(4.2%)因小肠梗阻入院,1例(4.2%)因新鲜直肠出血入院。2例(8.3%)患者接受了CT引导下引流。1例患者在全身麻醉下进行了伤口积液引流,另1例患者进行了腹腔镜引流管置入。3例(12.5%)患者进行了剖腹手术,其中1例分离粘连,1例切除阑尾残端,1例引流多处积液。

结论

阴性阑尾切除率和再入院率高得令人无法接受,需要降低。使用评分系统并引入治疗路径以尽量减少手术差异可能是降低NAR的一种策略。需要引入新的反馈系统以改善治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee3/7767194/d1514a69785a/life-10-00358-g001.jpg

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