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胃肠道:一个被忽视的守护天使?

Gastrointestinal Tract: A Neglected Guardian Angel?

作者信息

Kothekar Amol T, Kulkarni Atul P

机构信息

Division of Critical Care Medicine, Department of Anesthesia, Critical Care and Pain, Tata Memorial Center, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

Indian J Crit Care Med. 2020 Sep;24(Suppl 4):S146-S151. doi: 10.5005/jp-journals-10071-23616.

Abstract

Role of the gastrointestinal (GI) system is not limited to the digestion of food and absorption of water and nutrients. Gastrointestinal mucosa forms a barrier preventing translocation of microbes into the blood. Upper GI tract performs important function of swallowing and prevention of aspiration, failure of which mandates enteral tube feeding. Rate of gastric emptying depends on gastric volume and contents and delayed emptying is observed both in solid and in fatty food. Cricoid pressure during intubation is an important intervention for prevention of aspiration in critically ill patients who are considered as full stomach. To utilize mucosal barrier function optimally, hemodynamically stable patients should preferably receive enteral nutrition even if they are on small doses of vasopressors. Post-pyloric feeds may reduce risk of aspiration and hence are recommended for patients who are deemed to have high risk for aspiration. Bowel sounds have poor reproducibility, sensitivity, specificity, accuracy, and interobserver agreement, and absent bowel sounds should not be considered as a contraindication to enteral feeding. Kothekar AT, Kulkarni AP. Gastrointestinal Tract: A Neglected Guardian Angel? Indian J Crit Care Med 2020;24(Suppl 4):S146-S151.

摘要

胃肠道(GI)系统的作用不仅限于食物消化以及水和营养物质的吸收。胃肠道黏膜形成一道屏障,可防止微生物进入血液。上消化道执行吞咽和预防误吸的重要功能,若此功能出现障碍,则需进行肠内管饲。胃排空速率取决于胃容量和内容物,固体食物和脂肪类食物均会出现胃排空延迟的情况。插管时施加环状软骨压力是预防被视为饱胃的重症患者发生误吸的一项重要干预措施。为了最佳利用黏膜屏障功能,血流动力学稳定的患者即使使用小剂量血管升压药,也最好接受肠内营养。幽门后喂养可降低误吸风险,因此推荐用于被认为有误吸高风险的患者。肠鸣音的可重复性、敏感性、特异性、准确性及观察者间一致性较差,肠鸣音消失不应被视为肠内喂养的禁忌证。Kothekar AT,Kulkarni AP。胃肠道:一个被忽视的守护天使?《印度重症监护医学杂志》2020年;24(增刊4):S146 - S151。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd57/7724944/994948929037/ijccm-24-S146-g001.jpg

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