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菲尼亚斯·盖奇的伟大遗产。

Phineas Gage's great legacy.

作者信息

Teles Ricardo Vieira

机构信息

Faculty of Medicine, Universidade Federal de Goiás - Goiânia, GO, Brazil.

出版信息

Dement Neuropsychol. 2020 Dec;14(4):419-421. doi: 10.1590/1980-57642020dn14-040013.

DOI:10.1590/1980-57642020dn14-040013
PMID:33354296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7735047/
Abstract

The case of Phineas Gage is an integral part of medical folklore. His accident still causes astonishment and curiosity and can be considered as the case that most influenced and contributed to the nineteenth century's neuropsychiatric discussion on the mind-brain relationship and brain topography. It was perhaps the first case to suggest the role of brain areas in determining personality and which specific parts of the brain, when affected, can induce specific mental changes. In addition, his case contributed to the emergence of the scientific approaches that would later culminate in psychosurgery. Gage is a fixed element in the studies of neurology, psychology, and neuroscience, having been solidified as one of the greatest medical curiosities of all time, deserving its prominence.

摘要

菲尼亚斯·盖奇的病例是医学传奇故事中不可或缺的一部分。他的事故至今仍令人惊讶和好奇,堪称对19世纪关于心脑关系和脑局部解剖学的神经精神病学讨论影响最大、贡献最多的病例。这可能是首个表明脑区在决定人格方面所起作用的病例,以及大脑哪些特定部位受到影响时会引发特定心理变化的病例。此外,他的病例推动了后来发展为精神外科手术的科学方法的出现。盖奇是神经学、心理学和神经科学研究中的一个固定元素,已然巩固为有史以来最令人称奇的医学案例之一,实至名归。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd6/7735047/ecc3a17e078e/1980-5764-dn-14-04-0419-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd6/7735047/6d2b6530c4f5/1980-5764-dn-14-04-0419-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd6/7735047/ecc3a17e078e/1980-5764-dn-14-04-0419-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd6/7735047/6d2b6530c4f5/1980-5764-dn-14-04-0419-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd6/7735047/ecc3a17e078e/1980-5764-dn-14-04-0419-gf02.jpg

相似文献

1
Phineas Gage's great legacy.菲尼亚斯·盖奇的伟大遗产。
Dement Neuropsychol. 2020 Dec;14(4):419-421. doi: 10.1590/1980-57642020dn14-040013.
2
Neuroscience Education Begins With Good Science: Communication About Phineas Gage (1823-1860), One of Neurology's Most-Famous Patients, in Scientific Articles.神经科学教育始于严谨的科学:关于菲尼亚斯·盖奇(1823 - 1860)的科学文章中的交流,他是神经学领域最著名的患者之一。
Front Hum Neurosci. 2022 Apr 28;16:734174. doi: 10.3389/fnhum.2022.734174. eCollection 2022.
3
[Phineas Gage and the enigma of the prefrontal cortex].[菲尼亚斯·盖奇与前额叶皮层之谜]
Neurologia. 2012 Jul-Aug;27(6):370-5. doi: 10.1016/j.nrl.2010.07.015. Epub 2010 Oct 2.
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Phineas among the phrenologists: the American crowbar case and nineteenth-century theories of cerebral localization.
J Neurosurg. 1995 Apr;82(4):672-82. doi: 10.3171/jns.1995.82.4.0672.
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The return of Phineas Gage: clues about the brain from the skull of a famous patient.菲尼亚斯·盖奇的回归:从一位著名患者的颅骨中探寻大脑的线索
Science. 1994 May 20;264(5162):1102-5. doi: 10.1126/science.8178168.
6
A wonderful journey through skull and brains: the travels of Mr. Gage's tamping iron.
Brain Cogn. 1986 Jan;5(1):67-107. doi: 10.1016/0278-2626(86)90062-x.
7
Rehabilitating Phineas Gage. rehabilitating Phineas Gage
Neuropsychol Rehabil. 2010 Oct;20(5):641-58. doi: 10.1080/09602011003760527. Epub 2010 May 1.
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Mapping connectivity damage in the case of Phineas Gage.菲尼亚斯·盖奇病例中的连接损伤定位。
PLoS One. 2012;7(5):e37454. doi: 10.1371/journal.pone.0037454. Epub 2012 May 16.
9
Phineas Gage's contribution to brain surgery.菲尼亚斯·盖奇对脑外科手术的贡献。
J Hist Neurosci. 1996 Apr;5(1):56-77. doi: 10.1080/09647049609525651.
10
The tale of Phineas Gage, digitally remastered.菲尼亚斯·盖奇的故事,数码修复版。
J Neurotrauma. 2004 May;21(5):637-43. doi: 10.1089/089771504774129964.

本文引用的文献

1
Phineas Gage and his frontal lobe-the "American Crowbar Case".
Arch Environ Occup Health. 2012;67(4):249-50. doi: 10.1080/19338244.2012.722469.
2
Mapping connectivity damage in the case of Phineas Gage.菲尼亚斯·盖奇病例中的连接损伤定位。
PLoS One. 2012;7(5):e37454. doi: 10.1371/journal.pone.0037454. Epub 2012 May 16.
3
[Phineas Gage and the enigma of the prefrontal cortex].[菲尼亚斯·盖奇与前额叶皮层之谜]
Neurologia. 2012 Jul-Aug;27(6):370-5. doi: 10.1016/j.nrl.2010.07.015. Epub 2010 Oct 2.
4
Dr. Harlow's famous case: the "impossible" accident of Phineas P. Gage.哈洛博士的著名病例:菲尼亚斯·P·盖奇的“离奇”事故。
Surgery. 1962 Dec;52:952-8.
5
Phineas Gage and the science of brain localisation.菲尼亚斯·盖奇与脑定位科学
J Neurol Neurosurg Psychiatry. 2001 Dec;71(6):761. doi: 10.1136/jnnp.71.6.761.
6
Phineas Gage's contribution to brain surgery.菲尼亚斯·盖奇对脑外科手术的贡献。
J Hist Neurosci. 1996 Apr;5(1):56-77. doi: 10.1080/09647049609525651.
7
Restoring Phineas Gage: a 150th retrospective.
J Hist Neurosci. 2000 Apr;9(1):46-66. doi: 10.1076/0964-704X(200004)9:1;1-2;FT046.
8
The return of Phineas Gage: clues about the brain from the skull of a famous patient.菲尼亚斯·盖奇的回归:从一位著名患者的颅骨中探寻大脑的线索
Science. 1994 May 20;264(5162):1102-5. doi: 10.1126/science.8178168.
9
Phineas among the phrenologists: the American crowbar case and nineteenth-century theories of cerebral localization.
J Neurosurg. 1995 Apr;82(4):672-82. doi: 10.3171/jns.1995.82.4.0672.