拉斯穆森脑炎：一种在老年人中的表现？
Rasmussen encephalitis: an older adult presentation?
作者信息
Alvim Ricardo Pires, Aguiar Patrick, Amado Daniel Kempel, Rocha Maria Sheila Guimarães, Rodriguez Roberta Diehl, Brucki Sonia Maria Dozzi
机构信息
Behavioral and Cognitive Neurology Unit, Department of Neurology, Universidade de São Paulo - São Paulo, SP, Brazil.
Department of Neurology, Hospital Santa Marcelina - São Paulo, SP, Brazil.
出版信息
Dement Neuropsychol. 2020 Dec;14(4):434-437. doi: 10.1590/1980-57642020dn14-040016.
UNLABELLED
Rasmussen encephalitis (RE) is a classic disorder in the child age group, and only 10% of cases are described in adults. We bring two proven cases of RE in older adults aged over 55 years.
OBJECTIVE
To describe the clinical characteristics, progression, diagnostic assessment, neuropathological findings, and treatment of RE in two clinical cases of patients over 55 years of age. Furthermore, we address progressive cognitive decline as an important feature of the RE presentation in older adults in association with focal epilepsy.
METHODS
This is a case series from two tertiary hospitals from São Paulo - Brazil. Retrospective data were collected from one case. Results: Two male individuals aged >55 years with clinical presentation of focal epilepsy along with progressive cognitive deterioration.
CONCLUSIONS
RE could be considered the cause of progressive cognitive decline in older adults, especially if focal epilepsy is described together with asymmetrical neuroimaging findings.
未标注
拉斯穆森脑炎（RE）是儿童年龄组中的一种典型疾病，仅有10%的病例见于成年人。我们报告两例确诊的55岁以上老年人的RE病例。
目的
描述两例55岁以上患者RE的临床特征、病程、诊断评估、神经病理学发现及治疗。此外，我们探讨了进行性认知衰退作为老年人RE伴局灶性癫痫表现的一个重要特征。
方法
这是来自巴西圣保罗两家三级医院的病例系列。从一个病例收集回顾性数据。结果：两名年龄>55岁的男性，临床表现为局灶性癫痫伴进行性认知恶化。
结论
RE可被视为老年人进行性认知衰退的病因，尤其是当局灶性癫痫与不对称神经影像学表现同时出现时。
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