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使用韦恩评分指数评估吉达甲状腺功能亢进疑似病例的患病率。

Prevalence of Suspected Cases of Hyperthyroidism in Jeddah by Using Wayne's Scoring Index.

作者信息

Qashqary Mohammed, Tobaiqy Mansour, Al-Sutari Manal M, Mujallad Alaa, Alsheikh Intisar

机构信息

Family Medicine, University of Jeddah, Jeddah, SAU.

Family and Community Medicine, University of Jeddah, Jeddah, SAU.

出版信息

Cureus. 2020 Nov 17;12(11):e11538. doi: 10.7759/cureus.11538.

DOI:10.7759/cureus.11538
PMID:33354482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7746325/
Abstract

Introduction Hyperthyroidism is one of the primary dysfunctional thyroid diseases that results from abnormally high thyroid hormone secretion. It leads to metabolic derangement that manifests as heightened vital functions and metabolism and hyperdynamic blood circulation. Hyperthyroidism jeopardizes one's quality of life and hampers the patient's job performance. The disease is chronic but diagnosable and treatable and can be kept under control medically. We aimed to estimate the prevalence of suspected hyperthyroidism cases among a population sample in Jeddah city by using Wayne's scoring and delineation of factors associated with the disease. Materials and methods A cross-sectional study design was used. A total of 346 participants were conveniently selected from two shopping malls in Jeddah city during a five-day health awareness campaign. The data were collected by certified physicians, according to Wayne's score inventory. Results The study included 194 women (56.1%) and 152 men (43.9%). The participants' ages ranged from 16 to 56 years. The Wayne's scores showed 80.6% were euthyroid, 18.2% equivocal, and 1.2% have hyperthyroidism. Bronchial asthma was significantly associated with hyperthyroidism in men, while obesity was significantly associated with hyperthyroidism in women. Age, gender, level of education, and family history of chronic diseases, including thyroid disorders, were not significantly associated with hyperthyroidism. Conclusions Wayne's scoring for hyperthyroidism, which is a noninvasive tool, in addition to its detection of hyperthyroidism cases, can predict patients with equivocal results or those that might be subclinical for further medical assessment and follow-up. A Wayne's score can give the results of hyperthyroidism comparable to the results obtained by biochemical investigations. This tool is not in common use, but it is quite useful and should be put into broader usage.

摘要

引言

甲状腺功能亢进症是主要的甲状腺功能失调疾病之一,由甲状腺激素分泌异常增多引起。它会导致代谢紊乱,表现为生命机能和新陈代谢增强以及血液循环亢进。甲状腺功能亢进症会损害患者的生活质量,影响其工作表现。该疾病是慢性的,但可诊断且可治疗,通过医学手段能够得到控制。我们旨在通过使用韦恩评分法并确定与该疾病相关的因素,来估计吉达市人群样本中疑似甲状腺功能亢进症病例的患病率。

材料与方法

采用横断面研究设计。在为期五天的健康宣传活动期间,从吉达市的两个购物中心方便地选取了346名参与者。数据由认证医生根据韦恩评分量表收集。

结果

该研究包括194名女性(56.1%)和152名男性(43.9%)。参与者年龄在16至56岁之间。韦恩评分显示,甲状腺功能正常者占80.6%,结果不明确者占18.2%,甲状腺功能亢进者占1.2%。支气管哮喘在男性中与甲状腺功能亢进症显著相关,而肥胖在女性中与甲状腺功能亢进症显著相关。年龄、性别、教育程度以及包括甲状腺疾病在内的慢性疾病家族史与甲状腺功能亢进症均无显著关联。

结论

韦恩甲状腺功能亢进症评分法作为一种非侵入性工具,除了能够检测出甲状腺功能亢进症病例外,还可以预测结果不明确或可能为亚临床状态的患者,以便进行进一步医学评估和随访。韦恩评分得出的甲状腺功能亢进症结果与生化检查结果相当。该工具并不常用,但非常有用,应更广泛地应用。