Gordon A, Rasmussen S A
Department of Psychiatry and Human Behavior, Brown University, Providence, R.I.
J Clin Psychiatry. 1988 Jan;49(1):27-8.
The authors present a case of coexisting obsessive-compulsive disorder (OCD) and bipolar affective disorder in which the obsessive-compulsive symptoms disappeared during episodes of mania and reappeared during periods of depression. Although patients with coexisting bipolar disorder and OCD are relatively rare, careful study of those patients may increase our understanding of the complex relationship between obsessive-compulsive symptoms and mood. Abnormalities in serotonergic neurotransmission have been postulated in both affective disorders and OCD and may provide important clues to the pathophysiology of OCD.
作者报告了一例同时存在强迫症（OCD）和双相情感障碍的病例，其中强迫症状在躁狂发作期间消失，在抑郁期间再次出现。虽然同时患有双相情感障碍和强迫症的患者相对较少，但对这些患者进行仔细研究可能会增进我们对强迫症状与情绪之间复杂关系的理解。血清素能神经传递异常在情感障碍和强迫症中均有被提出，可能为强迫症的病理生理学提供重要线索。
