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单孔腹腔镜手术治疗回结肠型克罗恩病:倾向评分匹配分析

Single-incision laparoscopic surgery (SILS) for the treatment of ileocolonic Crohn's disease: a propensity score-matched analysis.

作者信息

Celentano Valerio, Pellino Gianluca, Rottoli Matteo, Colombo Francesco, Sampietro Gianluca, Spinelli Antonino, Selvaggi Francesco

机构信息

Portsmouth Hospitals NHS Trust, Portsmouth, UK.

University of Portsmouth, Portsmouth, UK.

出版信息

Int J Colorectal Dis. 2021 Mar;36(3):605-608. doi: 10.1007/s00384-020-03821-6. Epub 2020 Dec 23.

Abstract

INTRODUCTION

Single-incision laparoscopic surgery (SILS) aims to minimize the surgical access trauma by reducing the number of abdominal incisions to a single site, potentially offering better cosmetic results and decreased postoperative pain. In this study, we compare the results of SILS ileocolic resection for Crohn's disease (CD) to conventional laparoscopy and open surgery using a propensity score-matched analysis in a retrospective national multicentre study.

METHODS

All consecutive patients undergoing elective SILS ileocaecal or redo ileocolic resection for primary and recurrent CD from 1 June 2018 to 31 May 2019 were included. Patients were matched 1:1:1 with laparoscopy and open surgery according to perianal disease, recurrent disease, penetrating phenotype of CD, history of previous abdominal surgery, preoperative medical treatment with steroids and anti-TNF. Postoperative morbidity within 30 days of surgery was the primary endpoint.

RESULTS

Fifty-eight patients were included in each group, for a total of 174 patients. The conversion rate for SILS and laparoscopy was 10.3% and 12%, respectively, with no difference in the incidence of postoperative complications (13.8% and 12%, p = 0.77), whilst open surgery demonstrated a worse morbidity profile, with a complication rate of 25.9% (p < 0.0001). Median length of hospital stay following SILS ileocolic resection was 5 days, significantly shorter compared to 7 days for laparoscopy and 9 for open surgery (p < 0.0001).

CONCLUSIONS

SILS ileocolonic resection for CD demonstrated a comparable morbidity profile compared to laparoscopy in selected patients, with a reduced length of postoperative hospital stay.

摘要

引言

单孔腹腔镜手术(SILS)旨在通过将腹部切口数量减少至单个部位来最小化手术入路创伤,可能带来更好的美容效果并减轻术后疼痛。在本研究中,我们在一项回顾性全国多中心研究中使用倾向评分匹配分析,比较了SILS治疗克罗恩病(CD)的回结肠切除术与传统腹腔镜手术和开放手术的结果。

方法

纳入2018年6月1日至2019年5月31日期间所有因原发性和复发性CD接受择期SILS回盲部或再次回结肠切除术的连续患者。根据肛周疾病、复发性疾病、CD的穿透性表型、既往腹部手术史、术前使用类固醇和抗TNF药物治疗情况,将患者按1:1:1与腹腔镜手术和开放手术进行匹配。手术30天内的术后发病率是主要终点。

结果

每组纳入58例患者,共174例患者。SILS和腹腔镜手术的中转率分别为10.3%和12%,术后并发症发生率无差异(分别为13.8%和12%,p = 0.77),而开放手术的发病率更高,并发症发生率为25.9%(p < 0.0001)。SILS回结肠切除术后的中位住院时间为5天,明显短于腹腔镜手术的7天和开放手术的9天(p < 0.0001)。

结论

在选定患者中,SILS治疗CD的回结肠切除术与腹腔镜手术相比,发病率相当,术后住院时间缩短。

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