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既往多次开腹手术后克罗恩病患者的腹腔镜再次回结肠切除术

Laparoscopic Redo Ileocolic Resection for Crohn's Disease in Patients with Previous Multiple Laparotomies.

作者信息

Celentano V, Sagias F, Flashman K G, Conti J, Khan J

机构信息

Colorectal Unit, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth, UK.

出版信息

Scand J Surg. 2019 Mar;108(1):42-48. doi: 10.1177/1457496918772370. Epub 2018 May 10.

Abstract

PURPOSES

: Over 80% of patients with primary ileocolic Crohn's disease have a surgical resection within 10 years of diagnosis, and 40%-50% of them need further surgery within 15 years. Laparoscopic surgery can be challenging due to a thickened mesentery and the potential for fistulas, abscesses, and phlegmons. Aim of this study is to analyze the short-term outcomes of laparoscopic redo ileocolic resections for Crohn's disease in patients with previous multiple laparotomies.

METHODS

: All patients undergoing laparoscopic surgery for ileocolic Crohn's disease from March 2006 to February 2017 were prospectively evaluated. Short term outcomes of laparoscopic ileocolic resection were compared between patients with previous multiple major surgeries and recurrent Crohn's disease, and patients undergoing surgery for the first presentation of Crohn's disease and no history of previous surgery. Conversion rate and 30-day morbidity were the primary outcomes. Reoperations, readmissions, operating time and length of stay were the secondary outcomes.

RESULTS

: 29 patients with recurrent Crohn's disease and previous multiple laparotomies were included: the number of laparotomies these patients previously underwent was 2 in 19 cases (65.5%), 3 in 9 (31%), and 4 in 1 (3.5%). In total, 90 patients with no history of any previous abdominal surgery, who underwent laparoscopic ileocecal resection for Crohn's disease, represented the control group. No differences were found in morbidity and conversion rate. Operating time was longer in patients with history of previous abdominal surgery.

CONCLUSION

: Laparoscopic redo ileocolic resection for Crohn's disease is feasible and safe in patients with previous multiple laparotomies at the expense of longer operating time.

摘要

目的

超过80%的原发性回结肠型克罗恩病患者在确诊后10年内接受手术切除,其中40%-50%的患者在15年内需要再次手术。由于肠系膜增厚以及存在瘘管、脓肿和蜂窝织炎的可能性,腹腔镜手术具有挑战性。本研究的目的是分析既往多次开腹手术的克罗恩病患者行腹腔镜再次回结肠切除术的短期结局。

方法

对2006年3月至2017年2月期间接受腹腔镜回结肠型克罗恩病手术的所有患者进行前瞻性评估。比较既往有多次大手术和复发性克罗恩病的患者与首次因克罗恩病接受手术且无既往手术史的患者腹腔镜回结肠切除术的短期结局。主要结局为中转率和30天发病率。再次手术、再次入院、手术时间和住院时间为次要结局。

结果

纳入29例复发性克罗恩病且既往有多次开腹手术的患者:这些患者既往开腹手术的次数为19例(65.5%)2次,9例(31%)3次,1例(3.5%)4次。共有90例无既往腹部手术史、因克罗恩病接受腹腔镜回盲部切除术的患者作为对照组。在发病率和中转率方面未发现差异。既往有腹部手术史的患者手术时间更长。

结论

对于既往有多次开腹手术的克罗恩病患者,腹腔镜再次回结肠切除术是可行且安全的,但代价是手术时间更长。

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